Utility of 2-Chloro- N -arylacetamide and 1,1'-(Piperazine-1,4-diyl)bis(2-chloroethanone) as Versatile Precursors for Novel Mono- and Bis[thienopyridines].

Autor:	Salem ME; Department of Chemistry, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11623, Saudi Arabia.; Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt., Abdullah AH; Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt., Zaki MEA; Department of Chemistry, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11623, Saudi Arabia., Abdelhamid IA; Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt., Elwahy AHM; Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt.
Jazyk:	angličtina
Zdroj:	ACS omega [ACS Omega] 2024 Feb 21; Vol. 9 (9), pp. 10146-10159. Date of Electronic Publication: 2024 Feb 21 (Print Publication: 2024).
DOI:	10.1021/acsomega.3c06653
Abstrakt:	A series of novel thieno[2,3- b ]pyridines linked to N -aryl carboxamides or (carbonylphenoxy)- N -(aryl)acetamides, as well as bis(thieno[2,3- b ]pyridines) linked to piperazine core via methanone or carbonylphenoxyethanone units, were synthesized by treating the appropriate chloroacetyl- or bis-bromoacetyl derivatives with 2-mercaptonicotinonitrile derivatives in ethanolic sodium ethoxide at reflux. The spectral data were used to determine the compositions of novel compounds. Competing Interests: The authors declare no competing financial interest. (© 2024 The Authors. Published by American Chemical Society.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu