A rare case of schwannomatosis with meningioma: a case report.

Autor:	Neupane S; Institute of Medicine, Maharajgunj Medical Campus, Maharajgunj., Kashyap A; Institute of Medicine, Maharajgunj Medical Campus, Maharajgunj., Paudel S; Institute of Medicine, Maharajgunj Medical Campus, Maharajgunj., Bhattarai G; Institute of Medicine, Maharajgunj Medical Campus, Maharajgunj., Kharel SK; Institute of Medicine, Maharajgunj Medical Campus, Maharajgunj., Adhikari A; Institute of Medicine, Maharajgunj Medical Campus, Maharajgunj., Ghimire A; Institute of Medicine, Maharajgunj Medical Campus, Maharajgunj., Pokharel S; Institute of Medicine, Maharajgunj Medical Campus, Maharajgunj., Yadav P; Kathmandu Medical College And Teaching Hospital., Yadav KK; Department of General Surgery, Tribhuvan University Teaching Hospital, Kathmandu, Nepal.
Jazyk:	angličtina
Zdroj:	Annals of medicine and surgery (2012) [Ann Med Surg (Lond)] 2024 Jan 18; Vol. 86 (3), pp. 1724-1728. Date of Electronic Publication: 2024 Jan 18 (Print Publication: 2024).
DOI:	10.1097/MS9.0000000000001738
Abstrakt:	Introduction: Schwannomatosis is characterized by multiple schwannomas without vestibular schwannomas or any other stigmata of neurofibromatosis type 2 (NF2). Schwannomatosis is a rare disorder, with a reported incidence ranging from 1 in 40 000 to 1 in 1.7 million. Meningioma is also associated with schwannomatosis in around 5% of cases. Case Presentation: We describe a case of a 20-year-old female presenting with progressive weakness of the right lower limb for 7 months with a tingling sensation and numbness of the same limb for 6 months and was found to have schwannomatosis with multiple spinal and right cerebellopontine angle (CPA) (9th/10th cranial nerve) schwannomas and left anterior cranial fossa meningioma. Discussion: Schwannomas in schwannomatosis are seen along the cranial, spinal, and peripheral nerves but not along the vestibular nerve, as is characteristically seen in NF2. The occurrence of meningiomas is about 5% in individuals with schwannomatosis, and the patient in our case also had an associated meningioma. The tumor was confirmed to be a schwannoma based on features on an MRI examination and histological examination. Conclusion: It is of great significance to identify the entire spectrum of the disease in a patient with schwannomatosis, and to differentiate it from related conditions in order to track and surgically manage the patient appropriately based on symptomatology and imaging findings. Competing Interests: The authors declare no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article. (Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc.)
Databáze:	MEDLINE
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