Effect of Mosquitocidal, histopathological alteration and non target effects of Sigesbeckia orientalis L. on Anopheles stephensi Liston, Culex quinquefasciatus say and Aedes aegypti L.

Autor: Ragavendran K; Interdisciplinary Research Centre in Biology, Xavier Research Foundation, St. Xavier's College (Manonmaniam Sundaranar University), Palayamkottai, Tirunelveli, Tamilnadu, India., Selvakumaran J; Interdisciplinary Research Centre in Biology, Xavier Research Foundation, St. Xavier's College (Manonmaniam Sundaranar University), Palayamkottai, Tirunelveli, Tamilnadu, India., MuthuKanagavel M; Interdisciplinary Research Centre in Biology, Xavier Research Foundation, St. Xavier's College (Manonmaniam Sundaranar University), Palayamkottai, Tirunelveli, Tamilnadu, India., Ignacimuthu S; Interdisciplinary Research Centre in Biology, Xavier Research Foundation, St. Xavier's College (Manonmaniam Sundaranar University), Palayamkottai, Tirunelveli, Tamilnadu, India; The Anna and Donald Waite Chair, Creighton University, Omaha, United States of America. Electronic address: xrfsxc@gmail.com., Alharbi NS; Department of Botany and Microbiology, College of Science, King Saud University, P. O. Box 2455, Riyadh 11451, Saudi Arabia., Thiruvengadam M; Department of Crop Science, College of Sanghuh Life Sciences, Konkuk University, Seoul 05029, South Korea., Mutheeswaran S; Interdisciplinary Research Centre in Biology, Xavier Research Foundation, St. Xavier's College (Manonmaniam Sundaranar University), Palayamkottai, Tirunelveli, Tamilnadu, India., Ganesan P; Interdisciplinary Research Centre in Biology, Xavier Research Foundation, St. Xavier's College (Manonmaniam Sundaranar University), Palayamkottai, Tirunelveli, Tamilnadu, India. Electronic address: pathalamganesan@stxavierstn.edu.in.
Jazyk: angličtina
Zdroj: Veterinary parasitology, regional studies and reports [Vet Parasitol Reg Stud Reports] 2024 Apr; Vol. 49, pp. 100997. Date of Electronic Publication: 2024 Feb 03.
DOI: 10.1016/j.vprsr.2024.100997
Abstrakt: Diseases transmitted by vectors have a significant collision on society and community health, particularly in tropical and subtropical regions, where they can cause large-scale outbreaks shortly after initial transmission. The intent of this investigation was to study the plant extract derived from Sigesbeckia orientalis L. in controlling the immature stages of Anopheles, Culex and Aedes mosquitoes, while also considering its potential toxicity to ecosystems. The immature stages were exposed to different extracts (62.5-500 ppm), and the mortality of larvae and pupae, as well as ovicidal activity, were noted after 24 and 120 h of the experiment. The hexane and ethyl aceate extract of S. orientalis presented 100% ovicidal activity against the eggs of Anopheles, Aedes and Culex at 500 ppm concentration after 5 days of treatment. The hexane and ethylacetate extracts presented strong larvicidal activity with LC 50 values of 215.7, 332.0, 197.4 and 212.6, 694.9 and 201.7 ppm against treated mosquitoes at 24 h, respectively. The same extract also presented promising pupicidal activity. The LC 50 values of hexane extract were 219.6, 353.6, 194.2 and LC 50 values of ethyl acetate were 257.6, 387.8 and 259.07 ppm against early stage pupae of three vector mosquitoes, respectively. The extracts from S. orientalis had strong inhibitory activity against growth and development of mosquitoes. SI/PSF values showed that the extracts of S. orientalis did not harm Poecilia reticulata, Diplonychus indicus (Water bug), Gambusia affinis and dragon fly nymph at tested concentrations. Furthermore, examinations of histopathology and growth disruption revealed significant damage to the midgut cells in the treated larvae. The formulations utilizing hexane and ethyl acetate extracts exhibited potent activity without posing any toxicity towards non-target organisms. This study clearly indicated that hexane and ethylacetate extracts showed promising results against treated mosquitoes. The present study documents the first report of the extracts from S. orientalis and they can be further assessed to identify compounds for application purposes.
Competing Interests: Declaration of competing interest The authors declare that they have no conflict of interest.
(Copyright © 2024 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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