Dietary restriction modulates ultradian rhythms and autocorrelation properties in mice behavior.

Autor: Kembro JM; Universidad Nacional de Córdoba (UNC), Facultad de Ciencias Exactas, Físicas y Naturales, Instituto de Ciencia y Tecnología de los Alimentos (ICTA) and Departamento de Química, Cátedra de Química Biológica, Córdoba, Córdoba, X5000HUA, Argentina.; Instituto de Investigaciones Biológicas y Tecnológicas, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET)- UNC, Córdoba, Córdoba, X5000HUA, Argentina., Flesia AG; Universidad Nacional de Córdoba, Facultad de Matemática, Astronomía, Física y Computación, Córdoba, Córdoba, X5000HUA, Argentina.; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Centro de Investigaciones y Estudios de Matemática (CIEM, CONICET-UNC), Córdoba, Córdoba, X5000HUA, Argentina., Acosta-Rodríguez VA; Department of Neuroscience, Peter O'Donnell Jr. Brain Institute, University of Texas Southwestern Medical Center, Dallas, TX, 75390-9111, USA., Takahashi JS; Department of Neuroscience, Peter O'Donnell Jr. Brain Institute, University of Texas Southwestern Medical Center, Dallas, TX, 75390-9111, USA.; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX, 75390-9111, USA., Nieto PS; Universidad Nacional de Córdoba, Facultad de Matemática, Astronomía, Física y Computación, Córdoba, Córdoba, X5000HUA, Argentina. paula.nieto@unc.edu.ar.; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Instituto de Física Enrique Gaviola (IFEG, CONICET-UNC), Universidad Nacional de Córdoba, Córdoba, Córdoba, X5000HUA, Argentina. paula.nieto@unc.edu.ar.
Jazyk: angličtina
Zdroj: Communications biology [Commun Biol] 2024 Mar 09; Vol. 7 (1), pp. 303. Date of Electronic Publication: 2024 Mar 09.
DOI: 10.1038/s42003-024-05991-3
Abstrakt: Animal behavior emerges from integration of many processes with different spatial and temporal scales. Dynamical behavioral patterns, including daily and ultradian rhythms and the dynamical microstructure of behavior (i.e., autocorrelations properties), can be differentially affected by external cues. Identifying these patterns is important for understanding how organisms adapt to their environment, yet unbiased methods to quantify dynamical changes over multiple temporal scales are lacking. Herein, we combine a wavelet approach with Detrended Fluctuation Analysis to identify behavioral patterns and evaluate changes over 42-days in mice subjected to different dietary restriction paradigms. We show that feeding restriction alters dynamical patterns: not only are daily rhythms modulated but also the presence, phase and/or strength of ~12h-rhythms, as well as the nature of autocorrelation properties of feed-intake and wheel running behaviors. These results highlight the underlying complexity of behavioral architecture and offer insights into the multi-scale impact of feeding habits on physiology.
(© 2024. The Author(s).)
Databáze: MEDLINE
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