Hospitalisation for herpes zoster in people with and without diabetes: A 10-year-observational study.

Autor: Giorda CB; Metabolism and Diabetes Unit, ASL TO5, Regione Piemonte, Chieri, Italy. Electronic address: carlogiordaposta@gmail.com., Picariello R; Epidemiology Unit, ASL TO3, Regione Piemonte, Grugliasco, Italy., Tartaglino B; Chaira Medica Association, Chieri, Italy., Nada E; Metabolism and Diabetes Unit, ASL TO5, Regione Piemonte, Chieri, Italy., Romeo F; Metabolism and Diabetes Unit, ASL TO5, Regione Piemonte, Chieri, Italy., Costa G; Epidemiology Unit, ASL TO3, Regione Piemonte, Grugliasco, Italy; Department of Public Health, University of Torino, Torino, Italy., Gnavi R; Epidemiology Unit, ASL TO3, Regione Piemonte, Grugliasco, Italy.
Jazyk: angličtina
Zdroj: Diabetes research and clinical practice [Diabetes Res Clin Pract] 2024 Apr; Vol. 210, pp. 111603. Date of Electronic Publication: 2024 Mar 08.
DOI: 10.1016/j.diabres.2024.111603
Abstrakt: Aims: This study explores the association between Herpes Zoster (HZ) hospitalizations and diabetes in Piedmont, Italy from 2010 to 2019. Focusing on the burden of HZ hospitalizations in diabetic and non-diabetic groups, it aims to identify risk factors in diabetics to enhance prevention strategies.
Methods: In a two-phase study, we first compared age-standardized HZ hospitalization rates between diabetic and non-diabetic individuals from 2010 to 2019. We then examined hospitalization risk factors for HZ within a diabetic patient cohort managed by regional diabetes clinics.
Results: Of 3,423 HZ hospitalizations in 2010-2019, 17.9 % (613 cases) were diabetic patients, who exhibited higher hospitalization rates (15.9 to 6.0 per 100,000) compared to non-diabetese individuals. Among diabetics subjects risk factors for HZ hospitalization included age over 65, obesity (BMI > 30), and poor glycemic control (HbA1c > 8.0 %). These patients had a 40 % increased rehospitalization risk and a 25 % higher risk of severe complications, such as stroke and myocardial infarction, post-HZ.
Conclusions: Diabetes markedly increases HZ hospitalization rates, rehospitalization, and complication risks. These findings underscore the need for preventive strategies, especially improved glycemic control among high-risk diabetic patients, to inform public health policies and clinical practices aimed at mitigating HZ's impact on this population.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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