Predictive value of the Global Activity Limitation Indicator (GALI) on all-cause mortality.

Autor: Ayuso-Álvarez A; National Centre for Epidemiology, Institute of Health Carlos III, Spain; Department of Sociology, School of Economics, Universidad Autónoma de Madrid, Spain., Ortiz C; National Centre for Epidemiology, Institute of Health Carlos III, Spain., Fontán J; National Centre for Epidemiology, Institute of Health Carlos III, Spain., Rodríguez-Blázquez C; National Centre for Epidemiology, Institute of Health Carlos III, Spain., Damián J; National Centre for Epidemiology, Institute of Health Carlos III, Spain; Consortium for Biomedical Research in Neurodegenerative Diseases (CIBERNED), Spain., López-Cuadrado T; National Centre for Epidemiology, Institute of Health Carlos III, Spain; Department of Preventive Medicine and Public Health, School of Medicine, Universidad Autónoma de Madrid, Spain., Galán I; National Centre for Epidemiology, Institute of Health Carlos III, Spain; Department of Preventive Medicine and Public Health, School of Medicine, Universidad Autónoma de Madrid, Spain. Electronic address: igalan@isciii.es.
Jazyk: angličtina
Zdroj: Public health [Public Health] 2024 May; Vol. 230, pp. 6-11. Date of Electronic Publication: 2024 Mar 08.
DOI: 10.1016/j.puhe.2024.02.006
Abstrakt: Objectives: The Global Activity Limitation Indicator (GALI) is an instrument that measures long-term overall disability. The objective of this study was to evaluate GALI's predictive value on mortality while examining variations according to sex, age, and educational level.
Study Design: Longitudinal study.
Methods: This longitudinal study was based on 42,991 individuals aged ≥15 years who participated in the 2011-2012 National Health Survey and the 2014 European Health Survey in Spain. These records were linked to mortality data up to December 2021. GALI assessed self-reported functional limitation in the past 6 months and classified individuals into three categories: severely limited, limited but not severely, and not limited. Incidence rate ratios (IRR) were calculated using Poisson regression models, adjusting for sociodemographic, lifestyle, and health status variables.
Results: Compared to individuals with no limitations, those with non-severe limitations had an IRR for mortality of 1.27 (95% CI: 1.16-1.38), and 2.04 (95% CI: 1.81-2.31) in those with severe limitations. Women with severe limitations exhibited a higher IRR (2.32; 95% CI: 1.98-2.71) compared to men (1.73; 95% CI: 1.45-2.08) (P for interaction = 0.005). Individuals <65 years with severe limitations showed a greater association (2.22; 95% CI: 1.58-3.10) than those ≥65 (1.49; 95% CI: 1.32-1.69) (P for interaction <0.001). Among individuals with lower educational attainment, the IRR was 2.08 (95% CI: 1.83-2.37), and 1.87 (95% CI: 1.37-2.56) for the higher education group (P for interaction = 0.017).
Conclusions: GALI is a robust predictor of all-cause mortality in the general population and subgroups. The association is stronger in women, individuals <65 years, and those with lower educational levels.
(Copyright © 2024 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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