[New awareness for zoonoses using the example of rat bite fever : Case report and literature review].

Autor: Marschner M; Praxis Kardiologie Mitte, Charlottenstr. 63, 10117, Berlin, Deutschland. matthias.marschner@posteo.de., Hausdorf C; Abteilung Innere Medizin, Kardiologie, Sankt Gertrauden-Krankenhaus, Berlin, Deutschland., Lüno M; Abteilung Innere Medizin, Kardiologie, Sankt Gertrauden-Krankenhaus, Berlin, Deutschland., Schlatterer K; Institut für Laboratoriumsmedizin, Sankt Gertrauden-Krankenhaus, Berlin, Deutschland.; Medizinische Hochschule Brandenburg Theodor Fontane, Neuruppin, Deutschland.
Jazyk: němčina
Zdroj: Innere Medizin (Heidelberg, Germany) [Inn Med (Heidelb)] 2024 May; Vol. 65 (5), pp. 512-516. Date of Electronic Publication: 2024 Mar 08.
DOI: 10.1007/s00108-024-01680-9
Abstrakt: Background: Rat bite fever is a rare but potentially fatal bacterial zoonosis. The symptoms can be unspecific, but severe sepsis can be associated with involvement of different organs.
Case Report: A 27-year-old homeless man presented with fever, suspected meningitis, acute renal failure, unclear skin lesions as well as joint problems and muscular pain. Bite wounds were not detected. Meningitis could be excluded after lumbar puncture, and there was no evidence of endocarditis as the cause of the skin lesions. After 72 h, growth of Streptobacillus moniliformis in blood cultures was detected. Clinical symptoms were compatible with the diagnosis of rat bite fever. Calculated antibiosis with ampicillin sulbactam and doxycycline led to regression of the symptoms.
Conclusion: Rat bite fever poses a diagnostic challenge due unspecific symptoms, diverse differential diagnostic options, and challenging microbiological detection. Patient history is of the utmost importance. Due to the rarity of the disease, this case report is intended to raise awareness.
(© 2024. The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature.)
Databáze: MEDLINE
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