Prevalence of hearing loss, tinnitus, vertigo and sudden deafness among patients with polymyositis and dermatomyositis.

Autor: Hung SH; Department of Otolaryngology, School of Medicine, Taipei Medical University, Taipei, 110, Taiwan.; Department of Otolaryngology, Wan Fang Hospital, Taipei, 110, Taiwan.; International Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan., Xirasagar S; Department of Health Services Policy and Management, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA., Dang LH; Department of Otolaryngology, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam., Viet-Nhi NK; International Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan., Cheng YF; Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan.; Department of Otolaryngology-Head and Neck Surgery, Taipei Veterans General Hospital, Taipei, Taiwan.; Department of Otolaryngology-Head and Neck Surgery, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Research Center of Data Science on Healthcare Industry, College of Management, Taipei Medical University, Taipei, Taiwan., Chen CS; Research Center of Data Science on Healthcare Industry, College of Management, Taipei Medical University, Taipei, Taiwan. stan@mail.ntpu.edu.tw.; Department of Economics, National Taipei University, New Taipei City, Taiwan. stan@mail.ntpu.edu.tw., Lin HC; School of Health Care Administration, College of Management, Taipei Medical University, Taipei, Taiwan. henry11111@tmu.edu.tw.; Research Center of Sleep Medicine, Taipei Medical University Hospital, Taipei, Taiwan. henry11111@tmu.edu.tw.
Jazyk: angličtina
Zdroj: Scientific reports [Sci Rep] 2024 Mar 09; Vol. 14 (1), pp. 5774. Date of Electronic Publication: 2024 Mar 09.
DOI: 10.1038/s41598-024-56372-z
Abstrakt: Little is known about a possible association of autoimmune inner ear disease among patients diagnosed with polymyositis (PM)/dermatomyositis (DM). This study aimed to explore differences in the prevalence of inner ear symptoms among patients with and without PM/DM using a nationwide population-based dataset. Data for this study were retrieved from the Taiwan National Health Insurance Research Database. The study sample included 1622 patients diagnosed with PM/DM and 8109 propensity-score matched comparison patients without PM/DM. We performed multivariate logistic regressions to calculate odds ratios (ORs) and 95% confidence interval (CI) for tinnitus, hearing loss, sudden deafness, and vertigo among patients with PM/DM versus comparison patients. Chi-square tests showed statistically significant differences between patients with PM/DM and comparison patients in the prevalence of tinnitus (16.1% vs. 12.7%, p < 0.001), non-conductive hearing loss (9.2% vs. 6.8%, p < 0.001), and vertigo (14.4% vs. 11.1%, p < 0.001). The adjusted ORs for tinnitus, non-conductive hearing loss, and vertigo, respectively, were 1.332 (95% CI = 1.147-1.547), 1.399 (95% CI = 1.154-1.696), and 1.374 (95% CI = 1.173-1.611) for patients with PM/DM when compared to comparison patients. Our study finds that patients with PM/DM have higher prevalence rates of tinnitus, non-conductive hearing loss, and vertigo than comparison patients.
(© 2024. The Author(s).)
Databáze: MEDLINE
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