Localized surface plasmon resonance sensing of Trenbolone acetate dopant using silver nanoparticles.

Autor: Juma MW; UNESCO-UNISA Africa Chair in Nanoscience and Nanotechnology (U2ACN2), College of Graduate Studies, University of South Africa (UNISA), Pretoria, South Africa. jmwabwire@gmail.com.; NANOAFNET, iThemba LABS-National Research Foundation of South Africa, 1 Old Faure Road, Cape Town, 7129, Western Cape, South Africa. jmwabwire@gmail.com.; Department of Physics, University of South Africa, Muckleneuk Ridge, Pretoria, 0001, South Africa. jmwabwire@gmail.com.; Laser Physics and Spectroscopy Research Group, Department of Physics, University of Nairobi, P.O Box 30197-00100, Nairobi, Kenya. jmwabwire@gmail.com., Birech Z; Laser Physics and Spectroscopy Research Group, Department of Physics, University of Nairobi, P.O Box 30197-00100, Nairobi, Kenya., Mwenze NM; UNESCO-UNISA Africa Chair in Nanoscience and Nanotechnology (U2ACN2), College of Graduate Studies, University of South Africa (UNISA), Pretoria, South Africa.; NANOAFNET, iThemba LABS-National Research Foundation of South Africa, 1 Old Faure Road, Cape Town, 7129, Western Cape, South Africa.; Department of Physics, University of South Africa, Muckleneuk Ridge, Pretoria, 0001, South Africa.; Laser Physics and Spectroscopy Research Group, Department of Physics, University of Nairobi, P.O Box 30197-00100, Nairobi, Kenya., Ondieki AM; Laser Physics and Spectroscopy Research Group, Department of Physics, University of Nairobi, P.O Box 30197-00100, Nairobi, Kenya., Maaza M; UNESCO-UNISA Africa Chair in Nanoscience and Nanotechnology (U2ACN2), College of Graduate Studies, University of South Africa (UNISA), Pretoria, South Africa.; NANOAFNET, iThemba LABS-National Research Foundation of South Africa, 1 Old Faure Road, Cape Town, 7129, Western Cape, South Africa.; Department of Physics, University of South Africa, Muckleneuk Ridge, Pretoria, 0001, South Africa., Mokhotjwa SD; Department of Physics, University of South Africa, Muckleneuk Ridge, Pretoria, 0001, South Africa.
Jazyk: angličtina
Zdroj: Scientific reports [Sci Rep] 2024 Mar 08; Vol. 14 (1), pp. 5721. Date of Electronic Publication: 2024 Mar 08.
DOI: 10.1038/s41598-024-56456-w
Abstrakt: In this work, localized surface plasmon resonance (LSPR) sensing as applicable in the detection of Trenbolone acetate dopant is demonstrated. We show that the LSPR of the Trenbolone acetate/silver nanoparticle (Tren Ac/AgNPs) complex is sensitive to changes in the adsorbent concentration. The results show an average redshift of + 18 nm in the LSPR peak with variations in intensity and broadening behavior of the LSPR band of the Tren Ac/AgNPs complex. AgNPs were synthesized using laser ablation in liquid (LAL) technique with water as the solvent. UV-Vis spectroscopy was used for absorbance measurements and particle size and morphology were monitored using scanning electron microscopy (SEM). The aggregation behavior of the Tren Ac/AgNPs complex was monitored using energy-dispersive X-ray spectroscopy (EDS). Molecular Electrostatic Potential (MEP) and the HOMO-LUMO orbitals of the optimized Trenbolone acetate structure were obtained using Density Function Theory (DFT). The molecule was optimized at the B3LYP level of theory using the 6-311 basis set carried out using the Gaussian 09 software package. The results showed that O 2- is Trenbolone acetate's active site that would interact with Ag + to form a complex that would influence the plasmon behavior. The results presented in this work demonstrate the feasibility of LSPR for anabolic androgenic steroid detection.
(© 2024. The Author(s).)
Databáze: MEDLINE
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