Storage Conditions Influence the Quality of Ginger - A Stability Study Inspired by Clinical Trials.

Autor:	Tóth B; Institute of Pharmacognosy, University of Szeged, Szeged, Hungary.; Institute of Clinical Pharmacy, University of Szeged, Szeged, Hungary., Horváth A; Institute of Pharmacognosy, University of Szeged, Szeged, Hungary., Laczkovich OJ; Institute of Pharmaceutical Technology and Regulatory Affairs, University of Szeged, Szeged, Hungary., Biró ZD; Institute of Pharmacognosy, University of Szeged, Szeged, Hungary., Matuz M; Institute of Clinical Pharmacy, University of Szeged, Szeged, Hungary., Csupor D; Institute of Pharmacognosy, University of Szeged, Szeged, Hungary.; Institute of Clinical Pharmacy, University of Szeged, Szeged, Hungary.; Institute for Translational Medicine, University of Pécs, Pécs, Hungary.
Jazyk:	angličtina
Zdroj:	Planta medica [Planta Med] 2024 Aug; Vol. 90 (9), pp. 736-740. Date of Electronic Publication: 2024 Mar 08.
DOI:	10.1055/a-2283-8147
Abstrakt:	Ginger has traditionally been used to treat and prevent nausea and vomiting; however, the results of clinical trials are ambiguous. The efficacy of ginger is attributed to gingerols and their metabolites, shogaols. Since these compounds have different pharmacological profiles, the clinical efficacy of ginger products is largely dependent on their chemical composition. The goal of our study was to examine the stability of ginger, determining the 6-gingerol contents in order to assess the effects of different storage conditions. We have performed a 6-month stability test with dry ginger rhizome samples stored in a constant climate chamber in three different storage containers (uncovered glass container, glass container sealed with rubber stopper, and plastic container). The 6-gingerol contents were measured by HPLC method. The concentration of 6-gingerol decreased in all samples. In the sealed glass container, the decrease in 6-gingerol content was significantly lower than in the unsealed glass container and in the plastic container. These results demonstrate that storage conditions have a significant impact on the quality of ginger, which may also affect efficacy. Competing Interests: The authors declare no conflicts of interest. (Thieme. All rights reserved.)
Databáze:	MEDLINE
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