Extranodal Follicular Dendritic Cell Sarcoma Presenting on the Skin.

Autor: Agüero R; Facultad de Medicina Clínica Alemana - Universidad del Desarrollo, Santiago, Chile., Reculé F; Dermatology Service, Hospital Clínico de la Fuerza Aérea, Santiago, Chile.; Dermatology Service, Facultad de Medicina Clínica Alemana - Universidad del Desarrollo, Santiago, Chile ; and., Pérez J; Dermatology Service, Facultad de Medicina Clínica Alemana - Universidad del Desarrollo, Santiago, Chile ; and., Castro A; Department of Pathology, Facultad de Medicina Clínica Alemana - Universidad del Desarrollo, Santiago, Chile .
Jazyk: angličtina
Zdroj: The American Journal of dermatopathology [Am J Dermatopathol] 2024 Apr 01; Vol. 46 (4), pp. 218-222.
DOI: 10.1097/DAD.0000000000002639
Abstrakt: Abstract: Follicular dendritic cell sarcoma is a rare intermediate-grade malignancy characterized by a proliferation of ovoid to spindle-shaped cells with morphologic and immunophenotypic features similar to normal follicular dendritic cells. It may develop in lymph nodes or extranodal sites. Its presentation in extranodal tissues is a diagnostic challenge. It requires a high index of suspicion because follicular dendritic cell markers are not included in the routine immunohistochemical panels used for differential diagnosis. In an extensive review of the English literature, we found 3 cases of follicular dendritic cell sarcoma developing on the skin. We report a case of a primary cutaneous follicular dendritic cell sarcoma in a 28-year-old man, which presented as a 6-mm skin-colored nodule on the right forearm. We describe the morphologic and immunohistochemical features and a review of the literature.
Competing Interests: The authors declare no conflicts of interest.
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Databáze: MEDLINE