Learning ratio performance on a brief visual learning and memory test moderates cognitive training gains in Double Decision task in healthy older adults.

Autor: Hardcastle C; Center for Cognitive Aging and Memory, McKnight Brain Institute, University of Florida, Gainesville, FL, USA.; Department of Clinical and Health Psychology, College of Public Health and Health Professions, University of Florida, Gainesville, FL, USA., Kraft JN; Center for Cognitive Aging and Memory, McKnight Brain Institute, University of Florida, Gainesville, FL, USA.; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, USA., Hausman HK; Center for Cognitive Aging and Memory, McKnight Brain Institute, University of Florida, Gainesville, FL, USA.; Department of Clinical and Health Psychology, College of Public Health and Health Professions, University of Florida, Gainesville, FL, USA., O'Shea A; Center for Cognitive Aging and Memory, McKnight Brain Institute, University of Florida, Gainesville, FL, USA., Albizu A; Center for Cognitive Aging and Memory, McKnight Brain Institute, University of Florida, Gainesville, FL, USA.; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, USA., Evangelista ND; Center for Cognitive Aging and Memory, McKnight Brain Institute, University of Florida, Gainesville, FL, USA.; Department of Clinical and Health Psychology, College of Public Health and Health Professions, University of Florida, Gainesville, FL, USA., Boutzoukas EM; Center for Cognitive Aging and Memory, McKnight Brain Institute, University of Florida, Gainesville, FL, USA.; Department of Clinical and Health Psychology, College of Public Health and Health Professions, University of Florida, Gainesville, FL, USA., Van Etten EJ; Department of Psychology and Evelyn F. McKnight Brain Institute, University of Arizona, Tucson, AZ, USA., Bharadwaj PK; Department of Psychology and Evelyn F. McKnight Brain Institute, University of Arizona, Tucson, AZ, USA., Song H; Department of Psychology and Evelyn F. McKnight Brain Institute, University of Arizona, Tucson, AZ, USA., Smith SG; Department of Psychology and Evelyn F. McKnight Brain Institute, University of Arizona, Tucson, AZ, USA., Porges E; Center for Cognitive Aging and Memory, McKnight Brain Institute, University of Florida, Gainesville, FL, USA.; Department of Clinical and Health Psychology, College of Public Health and Health Professions, University of Florida, Gainesville, FL, USA., DeKosky ST; Department of Neurology and McKnight Brain Institute, University of Florida, Gainesville, FL, USA., Hishaw GA; Department Psychiatry, College of Medicine, University of Arizona, Tucson, AZ, USA.; Department of Neurology, College of Medicine, University of Arizona, Tucson, AZ, USA., Wu SS; Department of Biostatistics, College of Public Health and Health Professions, College of Medicine, University of Florida, Gainesville, FL, USA., Marsiske M; Center for Cognitive Aging and Memory, McKnight Brain Institute, University of Florida, Gainesville, FL, USA.; Department of Clinical and Health Psychology, College of Public Health and Health Professions, University of Florida, Gainesville, FL, USA., Cohen R; Center for Cognitive Aging and Memory, McKnight Brain Institute, University of Florida, Gainesville, FL, USA.; Department of Clinical and Health Psychology, College of Public Health and Health Professions, University of Florida, Gainesville, FL, USA., Alexander GE; Department of Psychology and Evelyn F. McKnight Brain Institute, University of Arizona, Tucson, AZ, USA.; Department of Psychiatry, Neuroscience and Physiological Sciences Graduate Interdisciplinary Programs, and BIO5 Institute, University of Arizona and Arizona Alzheimer's Disease Consortium, Tucson, AZ, USA., Woods AJ; Center for Cognitive Aging and Memory, McKnight Brain Institute, University of Florida, Gainesville, FL, USA. ajwoods@phhp.ufl.edu.; Department of Clinical and Health Psychology, College of Public Health and Health Professions, University of Florida, Gainesville, FL, USA. ajwoods@phhp.ufl.edu.; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, USA. ajwoods@phhp.ufl.edu.
Jazyk: angličtina
Zdroj: GeroScience [Geroscience] 2024 Aug; Vol. 46 (4), pp. 3929-3943. Date of Electronic Publication: 2024 Mar 08.
DOI: 10.1007/s11357-024-01115-1
Abstrakt: Cognitive training using a visual speed-of-processing task, called the Useful Field of View (UFOV) task, reduced dementia risk and reduced decline in activities of daily living at a 10-year follow-up in older adults. However, there was variability in the achievement of cognitive gains after cognitive training across studies, suggesting moderating factors. Learning trials of visual and verbal learning tasks recruit similar cognitive abilities and have overlapping neural correlates with speed-of-processing/working memory tasks and therefore could serve as potential moderators of cognitive training gains. This study explored the association between the Hopkins Verbal Learning Test-Revised (HVLT-R) and Brief Visuospatial Memory Test-Revised (BVMT-R) learning with a commercial UFOV task called Double Decision. Through a secondary analysis of a clinical trial, we assessed the moderation of HVLT-R and BVMT-R learning on Double Decision improvement after a 3-month speed-of-processing/attention and working memory cognitive training intervention in a sample of 75 cognitively healthy older adults. Multiple linear regressions showed that better baseline Double Decision performance was significantly associated with better BVMT-R learning (β =  - .303). This association was not significant for HVLT-R learning (β =  - .142). Moderation analysis showed that those with poorer BVMT-R learning improved the most on the Double Decision task after cognitive training. This suggests that healthy older adults who perform below expectations on cognitive tasks related to the training task may show the greatest training gains. Future cognitive training research studying visual speed-of-processing interventions should account for differing levels of visuospatial learning at baseline, as this could impact the magnitude of training outcomes and efficacy of the intervention.
(© 2024. The Author(s), under exclusive licence to American Aging Association.)
Databáze: MEDLINE
Externí odkaz: