Redefining treatment expectations: exploring mid- and long-term outcomes of venous sinus stenting in idiopathic intracranial hypertension.
Autor: | Midtlien JP; Department of Neurological Surgery, Atrium Wake Forest Baptist Health, Winston-Salem, North Carolina, USA jmidtlie@wakehealth.edu., Kittel C; Biostatistics, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA., Klever LA; Department of Neurological Surgery, Atrium Wake Forest Baptist Health, Winston-Salem, North Carolina, USA., Kiritsis NR; Department of Neurological Surgery, Atrium Wake Forest Baptist Health, Winston-Salem, North Carolina, USA., Aldridge JB; Department of Neurological Surgery, Atrium Wake Forest Baptist Health, Winston-Salem, North Carolina, USA., Fargen KM; Department of Neurological Surgery, Atrium Wake Forest Baptist Health, Winston-Salem, North Carolina, USA. |
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Jazyk: | angličtina |
Zdroj: | Journal of neurointerventional surgery [J Neurointerv Surg] 2024 Mar 07. Date of Electronic Publication: 2024 Mar 07. |
DOI: | 10.1136/jnis-2023-021336 |
Abstrakt: | Background: Venous sinus stenting (VSS) is recognized as a safe and effective intervention for medically-refractory idiopathic intracranial hypertension (IIH). However, its long-term efficacy remains uncertain. Methods: This retrospective review analyzed a single-center database of adult patients with severe, medically-refractory IIH, who underwent VSS and had minimum 3-month follow-up (FU). Patients were divided into three groups based on post-stenting symptom trajectories: group 1 (sustained improvement without relapse), group 2 (temporary improvement with relapse), and group 3 (no improvement). Results: Of 178 patients undergoing VSS, the majority were female (94%), with a median opening pressure (OP) of 31 cm H Conclusions: The most common clinical outcome post-VSS in IIH patients is initial symptomatic improvement followed by symptom recurrence in about 60% at a mean of 274 days, despite a consistent intracranial pressure reduction. These findings can guide physicians in setting realistic expectations with patients regarding VSS outcomes. Competing Interests: Competing interests: KMF serves on the editorial board of JNIS. (© Author(s) (or their employer(s)) 2024. No commercial re-use. See rights and permissions. Published by BMJ.) |
Databáze: | MEDLINE |
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