Multi-biobank summary data Mendelian randomisation does not support a causal effect of IL-6 signalling on risk of pulmonary arterial hypertension.

Autor: Woolf B; The MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK benjamin.woolf@bristol.ac.uk.; School of Psychological Science, University of Bristol, Bristol, UK.; The MRC Biostatistics Unit, University of Cambridge, Cambridge, UK., Perry JA; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Hong CC; Department of Medicine, Michigan State University College of Human Medicine, East Lansing, MI, USA., Wilkins MR; National Heart and Lung Institute, Imperial College London, London, UK., Toshner M; Department of Medicine, University of Cambridge, Cambridge, UK., Gill D; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Burgess S; The MRC Biostatistics Unit, University of Cambridge, Cambridge, UK.; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Rhodes CJ; National Heart and Lung Institute, Imperial College London, London, UK.
Jazyk: angličtina
Zdroj: The European respiratory journal [Eur Respir J] 2024 Apr 04; Vol. 63 (4). Date of Electronic Publication: 2024 Apr 04 (Print Publication: 2024).
DOI: 10.1183/13993003.02031-2023
Abstrakt: Competing Interests: Conflicts of interests: The authors declare no conflicts of interest.
Databáze: MEDLINE