An integrated approach to assess human health risk of neonicotinoid insecticides in surface water of the Yangtze River Basin, China.

Autor: Tsegay G; UNEP-TONGJI Institute of Environment for Sustainable Development (IESD), College of Environmental Science and Engineering, Tongji University, 1239 Siping Road, Shanghai 200092, China; Jiaxing-Tongji Environmental Research Institute, 1994 Linggongtang Road, Jiaxing 314051, Zhejiang Province, China., Lartey-Young G; UNEP-TONGJI Institute of Environment for Sustainable Development (IESD), College of Environmental Science and Engineering, Tongji University, 1239 Siping Road, Shanghai 200092, China., Sibhat M; UNEP-TONGJI Institute of Environment for Sustainable Development (IESD), College of Environmental Science and Engineering, Tongji University, 1239 Siping Road, Shanghai 200092, China., Gao Y; Jiaxing-Tongji Environmental Research Institute, 1994 Linggongtang Road, Jiaxing 314051, Zhejiang Province, China; Key Laboratory of Yangtze River Water Environment, Ministry of Education, College of Environmental Science and Engineering, Tongji University, 1239 Siping Road, Shanghai 200092, China; Shanghai Institute of Pollution Control and Ecological Security, Shanghai 200092, China., Guo LC; State Key Laboratory of Environmental Criteria and Risk Assessment, State Environmental Protection Key Laboratory of Ecological Effect and Risk Assessment of Chemicals, Chinese Research Academy of Environmental Sciences, Beijing 100012, China., Meng XZ; Jiaxing-Tongji Environmental Research Institute, 1994 Linggongtang Road, Jiaxing 314051, Zhejiang Province, China; Key Laboratory of Yangtze River Water Environment, Ministry of Education, College of Environmental Science and Engineering, Tongji University, 1239 Siping Road, Shanghai 200092, China; Shanghai Institute of Pollution Control and Ecological Security, Shanghai 200092, China. Electronic address: xzmeng@tongji.edu.cn.
Jazyk: angličtina
Zdroj: Journal of hazardous materials [J Hazard Mater] 2024 May 05; Vol. 469, pp. 133915. Date of Electronic Publication: 2024 Mar 02.
DOI: 10.1016/j.jhazmat.2024.133915
Abstrakt: Neonicotinoids are widely used insecticides that have raised considerable concerns for both environmental and human health. However, there lack of comprehensive evaluation of their accumulation in surface water ecosystems and exposure to various human groups. Additionally, there's a distinct lack of scientific evidence describing the carcinogenic and non-carcinogenic impacts of neonicotinoids from surface water. Using an integrated approach employing the Relative Potency Factor (RPF), Hazard Index (HI), and Monte Carlo Simulation (MCS), the study assessed neonicotinoid exposure and risk to four demographic groups via dermal contact and mistaken oral intake pathways in the Yangtze River Basin (YRB), China. Neonicotinoid concentrations range from 0.1 to 408.12 ng/L, indicating potential risk (10 -3 to 10 -1 ) across the studied demographic groups. The Incremental Lifetime Cancer Risk (ILCR) for dermal contact was within a moderate range of 2.00 × 10 -3 to 1.67 × 10 -2 , while the mistaken oral intake was also within a moderate range of 3.07 × 10 -3 to 7.05 × 10 -3 . The Hazard Index (HI) for dermal exposure ranged from 1.49 × 10 -2 to 0.125, while for mistaken oral intake, it varied between 2.69 × 10 -2 and 0.14. The findings highlight the importance of implementing specific interventions to address neonicotinoid exposure, especially among demographic groups that are more susceptible. This research underscores the urgent need for targeted strategies to address neonicotinoid risks to vulnerable populations within the YRB while contributing to insights for effective policies to mitigate neonicotinoid exposure in surface water ecosystems globally.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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