| Autor: |
Hossri CAC; Hospital do Coração, Associação Beneficente Síria, São Paulo, SP, Brasil.; Pneumologia-Incor, Instituto do Coração, Hospital das Clínicas (HCFMUSP), Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brasil., Araujo FC; FCA Sports, Belo Horizonte, MG, Brasil., Baldi BG; Hospital do Coração, Associação Beneficente Síria, São Paulo, SP, Brasil.; Pneumologia-Incor, Instituto do Coração, Hospital das Clínicas (HCFMUSP), Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brasil., Otterstetter R; School of Exercise and Nutrition Sciences, University of Akron, Akron, OH, USA., Uemoto VR; Setor da Bioengenharia, Instituto Dante Pazzanese, São Paulo, SP, Brasil., Carvalho CRR; Hospital do Coração, Associação Beneficente Síria, São Paulo, SP, Brasil.; Pneumologia-Incor, Instituto do Coração, Hospital das Clínicas (HCFMUSP), Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brasil., Mastrocola LE; Hospital do Coração, Associação Beneficente Síria, São Paulo, SP, Brasil., Albuquerque ALP; Hospital do Coração, Associação Beneficente Síria, São Paulo, SP, Brasil.; Pneumologia-Incor, Instituto do Coração, Hospital das Clínicas (HCFMUSP), Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brasil. |
| Abstrakt: |
There's limited evidence of the potential benefits of cardiopulmonary and metabolic rehabilitation (CPMR) in patients with heart failure with preserved ejection fraction (HFpEF) or mildly reduced ejection fraction (HFmrEF) and coronary artery disease (CAD). The aim of this study was to investigate the impact of CPMR on the myocardial ischemia response (MIR), exercise-induced arrhythmias (EIA), New York Heart Association (NYHA) functional class, heart rate recovery (HRR), Borg CR10 perceived symptoms, and the SF-36 physical and mental health summary scores. A prospective cohort study was conducted with 106 patients undergoing 12 weeks of CPMR who completed two exercise tests pre- and post-CPMR: 1) maximum incremental test (CPX) and 2) submaximal constant load test (SUB). After CPMR, the effects on MIR, EIA, NYHA functional class, and HRR during both tests were analyzed. There was a significant change in NYHA functional classes after CPMR, with 96% of the patients in class I (vs 62% pre-CPMR, P<0.0001), 4% in class II (vs 32%), and none in class III (vs 6%). There was a significant reduction in the frequency of EIA (P<0.05) and MIR (P<0.001) and a significantly improved performance on both CPX and SUB tests (P<0.0001). Lastly, there was significant progress in the recovery metrics like HRR (P<0.0001), the Borg CR10 (P<0.0001), and the SF-36 summary scores (P<0.0001). The CPMR resulted in a significant decrease in EIA, delayed ischemia threshold in CPX and SUB tests, increased functional capacity, and improved quality of life. |
