SARS-CoV-2 and Orientia tsutsugamushi co-infection in a young teen, Nepal: Significant burden in limited-resource countries in Asia?

Autor: Bastola A; Sukraraj Tropical and Infectious Disease Hospital, Teku, Kathmandu, Nepal., Sah R; Department of Microbiology, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal.; National Public Health Laboratory, Kathmandu, Nepal., Rajbhandari SK; Sukraraj Tropical and Infectious Disease Hospital, Teku, Kathmandu, Nepal., Jha R; National Public Health Laboratory, Kathmandu, Nepal., Fathah Z; King's College London, London, United Kingdom., Chalise BS; Sukraraj Tropical and Infectious Disease Hospital, Teku, Kathmandu, Nepal., Shrestha B; Sukraraj Tropical and Infectious Disease Hospital, Teku, Kathmandu, Nepal., Shah RK; Sukraraj Tropical and Infectious Disease Hospital, Teku, Kathmandu, Nepal., Balla P; Sukraraj Tropical and Infectious Disease Hospital, Teku, Kathmandu, Nepal., Nepal R; Sukraraj Tropical and Infectious Disease Hospital, Teku, Kathmandu, Nepal., Adhikari B; Nepal Community Health and Development Centre, Kathmandu, Nepal.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Rabaan AA; Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia., Dhama K; Division of Pathology, ICAR-Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh, India., Rodriguez-Morales AJ; Grupo de Investigación Biomedicina, Faculty of Medicine, Fundación Universitaria Autónoma de las Américas, Pereira, Risaralda, Colombia.; School of Medicine, Universidad Privada Franz Tamayo, Cochabamba, Bolivia.
Jazyk: angličtina
Zdroj: Narra J [Narra J] 2021 Aug; Vol. 1 (2), pp. e34. Date of Electronic Publication: 2021 Aug 01.
DOI: 10.52225/narraj.v1i2.34
Abstrakt: Scrub typhus is caused by Orientia tsutsugamushi , transmitted through bites of infected chiggers (larval mites). During the coronavirus disease 2019 (COVID-19) pandemic, reports of co-infections with endemic pathogens are increasing around the world. Disease with similar clinical presentation may mask other disease diagnosis and increase the morbidity and mortality of the patients. We report co-infection between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and O. tsutsugamushi in a patient in Nepal presenting with fever, headache, retro-orbital pain, generalized body ache, and knee joints pain with a history of dry cough and dyspnea at night. Since scrub typhus is prevalent and considerate as one of the public health consents in Asian countries and the possible overlapping clinical manifestation with other infections including COVID-19, a further investigation required to determine the burden of SARS-CoV-2 and O. tsutsugamushi co-infection in scrub typhus-endemic countries in Asia.
Competing Interests: Authors declare no conflict of interest.
(© 2021 The Author(s).)
Databáze: MEDLINE