The plasticity of immune memory in invertebrates.
| Autor: | Lanz-Mendoza H; Centro de Investigaciones sobre Enfermedades Infecciosas, INSP, 62100 Cuernavaca, Morelos, Mexico., Gálvez D; Coiba Scientific Station, City of Knowledge, Calle Gustavo Lara, Boulevard 145B, Clayton 0843-01853, Panama.; Programa Centroamericano de Maestría en Entomología, Universidad de Panamá, Estafeta universitaria, Avenida Simón Bolívar, 0824, Panama.; Sistema Nacional de Investigación, Edificio 205, Ciudad del Saber, 0816-02852, Panama., Contreras-Garduño J; Escuela Nacional de Estudios Superiores, Unidad Morelia, UNAM, 58190 Morelia, Mexico.; Institute for Evolution and Biodiversity, University of Münster, 48149 Münster, Germany. |
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| Jazyk: | angličtina |
| Zdroj: | The Journal of experimental biology [J Exp Biol] 2024 Mar 07; Vol. 227 (Suppl_1). Date of Electronic Publication: 2024 Mar 07. |
| DOI: | 10.1242/jeb.246158 |
| Abstrakt: | Whether specific immune protection after initial pathogen exposure (immune memory) occurs in invertebrates has long been uncertain. The absence of antibodies, B-cells and T-cells, and the short lifespans of invertebrates led to the hypothesis that immune memory does not occur in these organisms. However, research in the past two decades has supported the existence of immune memory in several invertebrate groups, including Ctenophora, Cnidaria, Nematoda, Mollusca and Arthropoda. Interestingly, some studies have demonstrated immune memory that is specific to the parasite strain. Nonetheless, other work does not provide support for immune memory in invertebrates or offers only partial support. Moreover, the expected biphasic immune response, a characteristic of adaptive immune memory in vertebrates, varies within and between invertebrate species. This variation may be attributed to the influence of biotic or abiotic factors, particularly parasites, on the outcome of immune memory. Despite its critical importance for survival, the role of phenotypic plasticity in immune memory has not been systematically examined in the past two decades. Additionally, the features of immune responses occurring in diverse environments have yet to be fully characterized. Competing Interests: Competing interests The authors declare no competing or financial interests. (© 2024. Published by The Company of Biologists Ltd.) |
| Databáze: | MEDLINE |
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