Nanocellulose-Based Hybrid Scaffolds for Skin and Bone Tissue Engineering: A 10-Year Overview.

Autor: Sreedharan M; International and Inter University Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam, Kerala 686560, India., Vijayamma R; International and Inter University Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam, Kerala 686560, India.; School of Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam, Kerala 686560, India., Liyaskina E; Department of Biotechnology, Biochemistry and Bioengineering, National Research Ogarev Mordovia State University, Saransk 430005, Russia., Revin VV; Department of Biotechnology, Biochemistry and Bioengineering, National Research Ogarev Mordovia State University, Saransk 430005, Russia., Ullah MW; Biofuels Institute, School of the Environment and Safety Engineering, Jiangsu University, Zhenjiang 212013, China., Shi Z; Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China., Yang G; Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China., Grohens Y; Univ. Bretagne Sud, UMR CNRS 6027, IRDL, F-56321 Lorient, France., Kalarikkal N; International and Inter University Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam, Kerala 686560, India.; School of Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam, Kerala 686560, India.; School of Pure and Applied Physics, Mahatma Gandhi University, Kottayam, Kerala 686560, India., Ali Khan K; Applied College, Mahala Campus and the Unit of Bee Research and Honey Production/Research Center for Advanced Materials Science (RCAMS), King Khalid University, Abha 61413, Saudi Arabia., Thomas S; International and Inter University Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam, Kerala 686560, India.; School of Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam, Kerala 686560, India.; School of Energy Materials, Mahatma Gandhi University, Kottayam, Kerala 686560, India.
Jazyk: angličtina
Zdroj: Biomacromolecules [Biomacromolecules] 2024 Apr 08; Vol. 25 (4), pp. 2136-2155. Date of Electronic Publication: 2024 Mar 06.
DOI: 10.1021/acs.biomac.3c00975
Abstrakt: Cellulose, the most abundant polymer on Earth, has been widely utilized in its nanoform due to its excellent properties, finding applications across various scientific fields. As the demand for nanocellulose continues to rise and its ease of use becomes apparent, there has been a significant increase in research publications centered on this biomaterial. Nanocellulose, in its different forms, has shown tremendous promise as a tissue engineered scaffold for regeneration and repair. Particularly, nanocellulose-based composites and scaffolds have emerged as highly demanding materials for both soft and hard tissue engineering. Medical practitioners have traditionally relied on collagen and its analogue, gelatin, for treating tissue damage. However, the limited mechanical strength of these biopolymers restricts their direct use in various applications. This issue can be overcome by making hybrids of these biopolymers with nanocellulose. This review presents a comprehensive analysis of the recent and most relevant publications focusing on hybrid composites of collagen and gelatin with a specific emphasis on their combination with nanocellulose. While bone and skin tissue engineering represents two areas where a majority of researchers are concentrating their efforts, this review highlights the use of nanocellulose-based hybrids in these contexts.
Databáze: MEDLINE