Retinal Vasculitis in a Patient with Hansen's Disease.
| Autor: | Savant SV; Beth Israel Lahey Health- Lahey Clinic, Burlington Massachusetts 01805, USA.; Tufts University, Boston Massachusetts 02111, USA., Soukiasian SH; Beth Israel Lahey Health- Lahey Clinic, Burlington Massachusetts 01805, USA.; Tufts University, Boston Massachusetts 02111, USA., Spaide RF; Vitreous-Retina-Macula Consultants of New York, New York, New York 10022, USA., Klein-Mascia KA; Beth Israel Lahey Health- Lahey Clinic, Burlington Massachusetts 01805, USA.; Tufts University, Boston Massachusetts 02111, USA. |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | Retinal cases & brief reports [Retin Cases Brief Rep] 2024 Mar 04. Date of Electronic Publication: 2024 Mar 04. |
| DOI: | 10.1097/ICB.0000000000001560 |
| Abstrakt: | Purpose: Hansen's disease is endemic in over 140 countries worldwide and a potentially blinding condition. We describe a case of retinal vasculitis in a patient with Hansen's disease with concomitant positive antiphospholipid antibody serology, a potentially under-reported complication in this setting. Methods: A 37-year-old Brazilian man systemically stable on triple therapy (clofazimine, rifampin, dapsone) for Hansen's disease presented for a comprehensive ophthalmic evaluation. Results: Dilated exam revealed diffuse peripheral intraretinal hemorrhages in his right eye. Fluorescein angiography showed peripheral non-perfusion, abnormal shunt vessels and leakage from the retinal veins in the right eye and peripheral non-perfusion and vascular leakage in the fellow eye, consistent with vasculitis. Laboratory workup was notable for positive antiphospholipid antibodies (lupus anticoagulant, anticardiolipin IgM, anti-beta-2 glycoprotein 1 IgM) and normocytic anemia. Conclusion: As antiphospholipid antibodies are present in a large proportion of patients with Hansen's disease, it is possible that retinal vasculitis may be more common than previously thought. The extent to which retinal vasculitis occurs in Hansen's disease remains uncertain and possibly underestimated due to the frequency of anterior segment scarring, which impedes retinal evaluation. Heightened surveillance for potential retinal vascular complications is warranted. |
| Databáze: | MEDLINE |
| Externí odkaz: |
|