Methylphenidate causes chronic eosinophilic pneumonia.

Autor: Alghamdi D; Department of Pulmonology, King Abdulaziz Medical City, Riyadh, Saudi Arabia., Jahdali H; Department of Pulmonology, King Abdulaziz Medical City, Riyadh, Saudi Arabia., Alharbi A; Department of Pulmonology, King Abdulaziz Medical City, Riyadh, Saudi Arabia., Alshehri A; Department of Psychiatry, King Abdulaziz Medical City, Riyadh, Saudi Arabia., Alfirm B; Department of Psychiatry, King Abdulaziz Medical City, Riyadh, Saudi Arabia., Bamefleh H; Department of Pathology and Laboratory Medicine, King Abdulaziz Medical City, Riyadh, Saudi Arabia.
Jazyk: angličtina
Zdroj: Annals of thoracic medicine [Ann Thorac Med] 2024 Jan-Mar; Vol. 19 (1), pp. 112-115. Date of Electronic Publication: 2024 Jan 25.
DOI: 10.4103/atm.atm_260_23
Abstrakt: A man who is 38 years old and diagnosed with attention-deficit hyperactivity disorder was prescribed methylphenidate. Three weeks later, he began experiencing progressive shortness of breath and coughing. Imaging of his chest showed patchy bilateral ground-glass opacities, and bronchoscopy revealed a 15% eosinophil count in his bronchoalveolar lavage. A transbronchial biopsy confirmed a diagnosis of eosinophilic pneumonia. The patient's condition improved when he was given steroids and stopped taking methylphenidate. However, he developed the same symptoms again a few days after restarting the medication, along with a skin rash. This strongly suggests that methylphenidate was the cause of his eosinophilic pneumonia.
Competing Interests: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work.
(Copyright: © 2024 Annals of Thoracic Medicine.)
Databáze: MEDLINE
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