Circumventing aglycon transfer en route to the synthesis of pentasaccharide thioglycoside donor for the chain extension of Plesiomonas shigelloides strain 302-73 (serotype O1) repeating unit.

Autor: Ghotekar BK; Department of Chemistry, Indian Institute of Technology Bombay, Powai, 400076, India., Biswas S; Department of Chemistry, Indian Institute of Technology Bombay, Powai, 400076, India., Kulkarni SS; Department of Chemistry, Indian Institute of Technology Bombay, Powai, 400076, India. Electronic address: suvarn@chem.iitb.ac.in.
Jazyk: angličtina
Zdroj: Carbohydrate research [Carbohydr Res] 2024 Mar; Vol. 537, pp. 109073. Date of Electronic Publication: 2024 Mar 01.
DOI: 10.1016/j.carres.2024.109073
Abstrakt: Herein we report a chemical synthesis of a pentasaccharide thioglycoside repeating unit of Plesiomonas shigelloides Strain 302-73 (Serotype O1), as a chain extension unit. In our synthetic endeavor we encountered multiple aglycon transfer reactions during glycosylations. This problem was obviated by employing a PMP group as a transient protecting group.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
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Databáze: MEDLINE
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