Reply to Kaestner et al.: Pioneering quantitative platforms for stored red blood cell assessment open the door for precision transfusion medicine.

Autor: Isiksacan Z; Department of Surgery, Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114.; Shriners Children's, Boston, MA 02114., D'Alessandro A; Department of Biochemistry and Molecular Genetics, University of Colorado Denver, Aurora, CO 80045., McKenna DH; Division of Transfusion Medicine, Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, MN 55455., Tessier SN; Department of Surgery, Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114.; Shriners Children's, Boston, MA 02114., Kucukal E; BioChip Labs, Cleveland, OH 44195., Gokaltun AA; Department of Surgery, Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114.; Shriners Children's, Boston, MA 02114.; Department of Chemical Engineering, Hacettepe University, Ankara 06532, Turkey., William N; Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB T6G 2R8, Canada., Sandlin RD; Department of Surgery, Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114., Bischof J; Department of Mechanical Engineering, University of Minnesota, Minneapolis, MN 55455.; Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455., Mohandas N; New York Blood Center, New York, NY 10065., Busch MP; Vitalant Research Institute, San Francisco, CA 94105.; Department of Laboratory Medicine, University of California, San Francisco, CA 94105., Elbuken C; Institute of Materials Science and Nanotechnology, National Nanotechnology Research Center, Bilkent University, Ankara 06800, Turkey.; Faculty of Biochemistry and Molecular Medicine, Faculty of Medicine, University of Oulu, Oulu 90014, Finland.; Valtion Teknillinen Tutkimuskeskus Technical Research Centre of Finland Ltd., Oulu 90570, Finland., Gurkan UA; Department of Mechanical and Aerospace Engineering, Case Western Reserve University, Cleveland, OH 44106.; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106.; Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH 44106., Toner M; Department of Surgery, Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114.; Shriners Children's, Boston, MA 02114., Acker JP; Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB T6G 2R8, Canada.; Innovation and Portfolio Management, Canadian Blood Services, Edmonton, AB T6G 2R8, Canada., Yarmush ML; Department of Surgery, Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114.; Shriners Children's, Boston, MA 02114.; Department of Biomedical Engineering, Rutgers University, Piscataway, NJ 08854., Usta OB; Department of Surgery, Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114.; Shriners Children's, Boston, MA 02114.
Jazyk: angličtina
Zdroj: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Mar 12; Vol. 121 (11), pp. e2320521121. Date of Electronic Publication: 2024 Mar 04.
DOI: 10.1073/pnas.2320521121
Abstrakt: Competing Interests: Competing interests statement:U.A.G. and Case Western Reserve University have financial interests in Hemex Health Inc. E.K., U.A.G., and Case Western Reserve University have financial interests in BioChip Labs Inc. U.A.G. and Case Western Reserve University have financial interests in Xatek Inc. U.A.G. has financial interests in DxNow Inc. Financial interests include licensed intellectual property, stock ownership, research funding, employment, and consulting. Hemex Health Inc. offers point-of-care diagnostics for hemoglobin disorders, anemia, and malaria. BioChip Labs Inc. offers commercial clinical microfluidic biomarker assays for inherited or acquired blood disorders. Xatek Inc. offers point-of-care global assays to evaluate the hemostatic process. DxNow Inc. offers microfluidic and bio-imaging technologies for in vitro fertilization, forensics, and diagnostics. Competing interests of Case Western Reserve University employees are overseen and managed by the Conflict of Interests Committee according to a Conflict-of-Interest Management Plan. The study was conducted prior to E.K. employment at IDEXX Laboratories, and the ideas expressed are not in his capacity as an IDEXX employee. A.D. serves on the Scientific Advisory Board of Hemanext Inc. and Macopharma Inc., and his competing interests are managed by the University of Colorado in accordance with their conflict-of-interest policies. S.N.T. and M.T. serve on the Scientific Advisory Board of Sylvatica Biotech Inc., a company focused on developing high subzero organ preservation technology. Competing interests for all authors affiliated with the Massachusetts General Hospital are managed by the MGH and Mass General Brigham in accordance with their conflict-of-interest policies. The remaining authors declare no competing interests.
Databáze: MEDLINE