| Autor: |
Karthik CS; Department of Chemistry, SJCE, JSS Science and Technology University, Karnataka, 570 006, Mysore, India.; Department of Chemistry, Khalifa University of Science and Technology, 127788, Abu Dhabi, United Arab Emirates. dinesh.shetty@ku.ac.ae.; Center for Catalysis and Separations (CeCaS), Khalifa University of Science and Technology, 127788, Abu Dhabi, United Arab Emirates., Skorjanc T; The Materials Research Laboratory, University of Nova Gorica, Vipavska 11c, 5270, Ajdovscina, Slovenia., Shetty D; Department of Chemistry, Khalifa University of Science and Technology, 127788, Abu Dhabi, United Arab Emirates. dinesh.shetty@ku.ac.ae.; Center for Catalysis and Separations (CeCaS), Khalifa University of Science and Technology, 127788, Abu Dhabi, United Arab Emirates. |
| Abstrakt: |
Fluorescent covalent organic frameworks (COFs) have emerged as promising candidates for imaging living cells due to their unique properties and adjustable fluorescence. In this mini-review, we provide an overview of recent advancements in fluorescent COFs for bioimaging applications. We discuss the strategies used to design COFs with desirable properties such as high photostability, excellent biocompatibility, and pH sensitivity. Additionally, we explore the various ways in which fluorescent COFs are utilized in bioimaging, including cellular imaging, targeting specific organelles, and tracking biomolecules. We delve into their applications in sensing intracellular pH, reactive oxygen species (ROS), and specific biomarkers. Furthermore, we examine how functionalization techniques enhance the targeting and imaging capabilities of fluorescent COFs. Finally, we discuss the challenges and prospects in the field of fluorescent COFs for bioimaging in living cells, urging further research in this exciting area. |
