Unveiling dysplasia epiphysealis hemimelica (Trevor's disease) in the foot and ankle: A systematic review.

Autor: Artioli E; IRCCS Istituto Ortopedico Rizzoli, Via Giulio Cesare Pupilli 1, 40136, Bologna, Italy.; 1st Orthopaedic and Traumatologic Clinic, Italy.; Department of Biomedical and Neuromotor Sciences, University of Bologna, 40123, Bologna, Italy., Mazzotti A; IRCCS Istituto Ortopedico Rizzoli, Via Giulio Cesare Pupilli 1, 40136, Bologna, Italy.; 1st Orthopaedic and Traumatologic Clinic, Italy.; Department of Biomedical and Neuromotor Sciences, University of Bologna, 40123, Bologna, Italy., De Pellegrin M; Pediatric Orthopedic Unit, Piccole Figlie Hospital, Parma, Italy.; Department of Orthopedics, ASST Ospedale Papa Giovanni XXIII, Bergamo, Italy., Arceri A; IRCCS Istituto Ortopedico Rizzoli, Via Giulio Cesare Pupilli 1, 40136, Bologna, Italy.; 1st Orthopaedic and Traumatologic Clinic, Italy., Zielli SO; IRCCS Istituto Ortopedico Rizzoli, Via Giulio Cesare Pupilli 1, 40136, Bologna, Italy.; 1st Orthopaedic and Traumatologic Clinic, Italy., Langone L; IRCCS Istituto Ortopedico Rizzoli, Via Giulio Cesare Pupilli 1, 40136, Bologna, Italy.; 1st Orthopaedic and Traumatologic Clinic, Italy., Faldini C; IRCCS Istituto Ortopedico Rizzoli, Via Giulio Cesare Pupilli 1, 40136, Bologna, Italy.; 1st Orthopaedic and Traumatologic Clinic, Italy.; Department of Biomedical and Neuromotor Sciences, University of Bologna, 40123, Bologna, Italy.
Jazyk: angličtina
Zdroj: Journal of orthopaedics [J Orthop] 2024 Feb 20; Vol. 52, pp. 49-54. Date of Electronic Publication: 2024 Feb 20 (Print Publication: 2024).
DOI: 10.1016/j.jor.2024.02.036
Abstrakt: Background: Dysplasia epiphysealis hemimelica is a rare non-inherited condition characterized by the unilateral predominance of osteochondromas in one or more epiphyses, with ankles and knees being the most affected joints. Treatment approaches vary based on the localization of the disease, encompassing both conservative and surgical options. Due to its rarity, there is a lack of definitive surgical guidelines or specific treatment modalities. Therefore, the objective of this systematic review was to thoroughly investigate dysplasia epiphysealis hemimelica to provide evidence-based guidance for managing this condition, specifically focusing on the foot and ankle.
Methods: A systematic search was performed on PubMed and the Cochrane Library to identify all published articles related to dysplasia epiphysealis hemimelica of the foot and ankle. Individual patient information, such as gender, age, disease type, follow-up, localization, clinical presentation, intervention, and complications, were systematically extracted from each article and analyzed.
Results: Twenty-five eligible publications were included in the review, involving a total of 70 patients (16 females, 53 males). The mean age was 9.6 years (SD 7.3). The talus was the most prevalent location and clinical presentations included mass and pain in 54% of cases. Surgical procedures were chosen in 92% of patients, with 95% undergoing mass excision. Recurrence was the most frequent complication, observed in 9% of cases.
Conclusions: Raising awareness about dysplasia epiphysealis hemimelica is crucial for early diagnosis and treatment, positively impacting clinical outcomes. Vigilant monitoring is essential during observational management, as unchecked mass growth can complicate surgical intervention. Surgical treatment focuses on mass excision, feasible even at a young age but requiring precision to prevent recurrence or secondary arthritis.
Level of Evidence: IV.
Competing Interests: None.
(© 2024 Professor P K Surendran Memorial Education Foundation. Published by Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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