Staphylococcus haemolyticus: An updated review on nosocomial infections, antimicrobial resistance, virulence, genetic traits, and strategies for combating this emerging opportunistic pathogen.

Autor: Rossi CC; Departamento de Bioquímica e Biologia Molecular, Universidade Federal de Viçosa, MG, Brazil. Electronic address: ciro.rossi@ufv.br., Ahmad F; Departamento de Bioquímica e Biologia Molecular, Universidade Federal de Viçosa, MG, Brazil., Giambiagi-deMarval M; Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro, RJ, Brazil.
Jazyk: angličtina
Zdroj: Microbiological research [Microbiol Res] 2024 May; Vol. 282, pp. 127652. Date of Electronic Publication: 2024 Feb 22.
DOI: 10.1016/j.micres.2024.127652
Abstrakt: Staphylococcus haemolyticus, a key species of the Staphylococcus genus, holds significant importance in healthcare-associated infections, due to its notable resistance to antimicrobials, like methicillin, and proficient biofilms-forming capabilities. This coagulase-negative bacterium poses a substantial challenge in the battle against nosocomial infections. Recent research has shed light on Staph. haemolyticus genomic plasticity, unveiling genetic elements responsible for antibiotic resistance and their widespread dissemination within the genus. This review presents an updated and comprehensive overview of the clinical significance and prevalence of Staph. haemolyticus, underscores its zoonotic potential and relevance in the one health framework, explores crucial virulence factors, and examines genetics features contributing to its success in causing emergent and challenging infections. Additionally, we scrutinize ongoing studies aimed at controlling spread and alternative approaches for combating it.
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Databáze: MEDLINE
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