Alzheimer's Disease Prevention and Treatment Based on Population-Based Approaches.
| Autor: | Perneczky R; Department of Psychiatry and Psychotherapy, LMU Hospital, Ludwig-Maximilians-Universität München, Munich, Germany. robert.perneczky@med.uni-muenchen.de.; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany. robert.perneczky@med.uni-muenchen.de.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany. robert.perneczky@med.uni-muenchen.de.; Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield, UK. robert.perneczky@med.uni-muenchen.de.; Ageing Epidemiology (AGE) Research Unit, School of Public Health, Imperial College London, London, UK. robert.perneczky@med.uni-muenchen.de. |
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| Jazyk: | angličtina |
| Zdroj: | Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2024; Vol. 2785, pp. 15-33. |
| DOI: | 10.1007/978-1-0716-3774-6_2 |
| Abstrakt: | The development of effective prevention and treatment strategies for Alzheimer's disease (AD) and dementia is hindered by limited knowledge of the underlying biological and environmental causes. While certain genetic factors have been associated with AD, and various lifestyle and environmental factors have been linked to dementia risk, the interactions between genes and the environment are not yet fully understood. To identify new avenues for dementia prevention, coordinated global efforts are needed to utilize existing cohorts and resources effectively and efficiently. This chapter provides an overview of current research on risk and protective factors for AD and dementia and discusses the opportunities and challenges associated with population-based approaches. (© 2024. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.) |
| Databáze: | MEDLINE |
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