Renal Congestion in Heart Failure: Insights in Novel Diagnostic Modalities.

Autor:	Dimitriadis K; From the First Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Hippokration General Hospital, Athens, Greece., Damianaki A; Nephrology Department, Hippokration Hospital, Athens, Greece., Bletsa E; 3rd Department of Cardiology, Sotiria Hospital, University of Athens, Athens, Greece., Pyrpyris N; From the First Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Hippokration General Hospital, Athens, Greece., Tsioufis P; From the First Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Hippokration General Hospital, Athens, Greece., Theofilis P; From the First Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Hippokration General Hospital, Athens, Greece., Beneki E; From the First Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Hippokration General Hospital, Athens, Greece., Tatakis F; From the First Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Hippokration General Hospital, Athens, Greece., Kasiakogias A; From the First Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Hippokration General Hospital, Athens, Greece., Oikonomou E; 3rd Department of Cardiology, Sotiria Hospital, University of Athens, Athens, Greece., Petras D; Nephrology Department, Hippokration Hospital, Athens, Greece., Siasos G; 3rd Department of Cardiology, Sotiria Hospital, University of Athens, Athens, Greece., Aggeli K; From the First Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Hippokration General Hospital, Athens, Greece., Tsioufis K; From the First Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Hippokration General Hospital, Athens, Greece.
Jazyk:	angličtina
Zdroj:	Cardiology in review [Cardiol Rev] 2024 Feb 29. Date of Electronic Publication: 2024 Feb 29.
DOI:	10.1097/CRD.0000000000000673
Abstrakt:	Heart failure is increasingly prevalent and is estimated to increase its burden in the following years. A well-reported comorbidity of heart failure is renal dysfunction, where predominantly changes in the patient's volume status, tubular necrosis or other mechanical and neurohormonal mechanisms seem to drive this impairment. Currently, there are established biomarkers evaluating the patient's clinical status solely regarding the cardiovascular or renal system. However, as the coexistence of heart and renal failure is common and related to increased mortality and hospitalization for heart failure, it is of major importance to establish novel diagnostic techniques, which could identify patients with or at risk for cardiorenal syndrome and assist in selecting the appropriate management for these patients. Such techniques include biomarkers and imaging. In regards to biomarkers, several peptides and miRNAs indicative of renal or tubular dysfunction seem to properly identify patients with cardiorenal syndrome early on in the course of the disease, while changes in their serum levels can also be helpful in identifying response to diuretic treatment. Current and novel imaging techniques can also identify heart failure patients with early renal insufficiency and assess the volume status and the effect of treatment of each patient. Furthermore, by assessing the renal morphology, these techniques could also help identify those at risk of kidney impairment. This review aims to present all relevant clinical and trial data available in order to provide an up-to-date summary of the modalities available to properly assess cardiorenal syndrome. Competing Interests: Disclosure: The authors have no conflicts of interest to report. (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)
Databáze:	MEDLINE
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