Flow control by circular cavities in lateral flow porous membranes.

Autor: Jamil SR; Faculty of Mechanical Engineering, University of Engineering and Technology, Lahore, Pakistan., Abbasi MS; Faculty of Mechanical Engineering, University of Engineering and Technology, Lahore, Pakistan., Jafry AT; Faculty of Mechanical Engineering, Ghulam Ishaq Khan Institute of Engineering Sciences and Technology, Topi, Pakistan., Shahzad T; Faculty of Mechanical Engineering, University of Engineering and Technology, Lahore, Pakistan., Sarwar S; Faculty of Mechanical Engineering, University of Engineering and Technology, Lahore, Pakistan., Qureshi MH; Faculty of Mechanical Engineering, University of Engineering and Technology, Lahore, Pakistan.
Jazyk: angličtina
Zdroj: Science progress [Sci Prog] 2024 Jan-Mar; Vol. 107 (1), pp. 368504241235508.
DOI: 10.1177/00368504241235508
Abstrakt: This research explores the flow penetration in porous media by virtue of capillary action and geometric control of the liquid imbibition rate in microfluidic paper-based analytical devices (μPADs) having applications in food quality management, medical diagnostics, and environmental monitoring. We examine changes in flow resistance and membrane geometry, aiming to understand factors influencing capillary penetration rates for various practical applications. We conducted experiments and simulations using lateral porous membranes and altered the flow resistance by changing the liquids or the paper channel geometry by adding cavities. From experiments, it was revealed that by creating a circular cavity in the paper channel, the penetration rate was sufficiently altered. Moreover, increasing the cavity size and type of liquid (w.r.t. viscosity) also caused a decrease in the flow rate. Imbibition rates were also influenced by the position of the cavities in the paper channel. The maximum delay for water was almost 2 times with a 16 mm circular cavity located at 3 cm from strip bottom edge. Overall, we attained a maximum delay in the case of castor oil which was almost 85 times slower than water and 3.7 times slower than olive oil. A good agreement was observed with CFD analysis. We believe that this research would help in developing advance techniques to enhance the flow control strategies in μPADs and indicators.
Competing Interests: Declaration of conflicting interestsThe authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Databáze: MEDLINE
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