Diagnosis and management of subarachnoid haemorrhage.

Autor: Thilak S; University Hospitals Birmingham NHS Foundation Trust, Queen Elizabeth Hospital, Birmingham, B15 2GW, UK., Brown P; University Hospitals Birmingham NHS Foundation Trust, Queen Elizabeth Hospital, Birmingham, B15 2GW, UK., Whitehouse T; University Hospitals Birmingham NHS Foundation Trust, Queen Elizabeth Hospital, Birmingham, B15 2GW, UK.; Institute of Inflammation and Ageing, University of Birmingham, Birmingham, B15 2TT, UK., Gautam N; University Hospitals Birmingham NHS Foundation Trust, Queen Elizabeth Hospital, Birmingham, B15 2GW, UK., Lawrence E; University Hospitals Birmingham NHS Foundation Trust, Queen Elizabeth Hospital, Birmingham, B15 2GW, UK.; Institute of Inflammation and Ageing, University of Birmingham, Birmingham, B15 2TT, UK., Ahmed Z; Institute of Inflammation and Ageing, University of Birmingham, Birmingham, B15 2TT, UK.; Centre for Trauma Sciences Research, University of Birmingham, Birmingham, B15 2TT, UK., Veenith T; Institute of Inflammation and Ageing, University of Birmingham, Birmingham, B15 2TT, UK. tonny.veenith1@nhs.net.; Centre for Trauma Sciences Research, University of Birmingham, Birmingham, B15 2TT, UK. tonny.veenith1@nhs.net.; Department of Critical Care Medicine and Anaesthesia, The Royal Wolverhampton NHS Foundation Trust, New Cross Hospital, Wolverhampton, WV10 0QP, UK. tonny.veenith1@nhs.net.
Jazyk: angličtina
Zdroj: Nature communications [Nat Commun] 2024 Feb 29; Vol. 15 (1), pp. 1850. Date of Electronic Publication: 2024 Feb 29.
DOI: 10.1038/s41467-024-46015-2
Abstrakt: Aneurysmal subarachnoid haemorrhage (aSAH) presents a challenge to clinicians because of its multisystem effects. Advancements in computed tomography (CT), endovascular treatments, and neurocritical care have contributed to declining mortality rates. The critical care of aSAH prioritises cerebral perfusion, early aneurysm securement, and the prevention of secondary brain injury and systemic complications. Early interventions to mitigate cardiopulmonary complications, dyselectrolytemia and treatment of culprit aneurysm require a multidisciplinary approach. Standardised neurological assessments, transcranial doppler (TCD), and advanced imaging, along with hypertensive and invasive therapies, are vital in reducing delayed cerebral ischemia and poor outcomes. Health care disparities, particularly in the resource allocation for SAH treatment, affect outcomes significantly, with telemedicine and novel technologies proposed to address this health inequalities. This article underscores the necessity for comprehensive multidisciplinary care and the urgent need for large-scale studies to validate standardised treatment protocols for improved SAH outcomes.
(© 2024. The Author(s).)
Databáze: MEDLINE
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