Racial and ethnic differences in uncontrolled diabetes mellitus among adults taking antidiabetic medication.

Autor: Berg KA; Center for Health Care Research and Policy, Population Health Research Institute, The MetroHealth System at Case Western Reserve University, Cleveland, OH, USA. Electronic address: kristen.berg@case.edu., Bharmal N; Community Health & Partnerships, Cleveland Clinic Community Care, Cleveland, OH, USA., Tereshchenko LG; Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, USA., Le P; Center for Value-Based Care Research, Cleveland Clinic Community Care, Cleveland, OH, USA., Payne JY; Center for Value-Based Care Research, Cleveland Clinic Community Care, Cleveland, OH, USA; Department of Population and Quantitative Health Sciences, Case Western Reserve University, School of Medicine, Cleveland, OH, USA., Misra-Hebert AD; Center for Value-Based Care Research, Cleveland Clinic Community Care, Cleveland, OH, USA; Healthcare Delivery & Implementation Science Center, Cleveland Clinic, Cleveland, OH, USA., Rothberg MB; Center for Value-Based Care Research, Cleveland Clinic Community Care, Cleveland, OH, USA.
Jazyk: angličtina
Zdroj: Primary care diabetes [Prim Care Diabetes] 2024 Jun; Vol. 18 (3), pp. 368-373. Date of Electronic Publication: 2024 Feb 29.
DOI: 10.1016/j.pcd.2024.02.004
Abstrakt: Aim: To examine whether racial and ethnic disparities in uncontrolled type 2 diabetes mellitus (T2DM) persist among those taking medication and after accounting for other demographic, socioeconomic, and health indicators.
Methods: Adults aged ≥20 years with T2DM using prescription diabetes medication were among participants assessed in a retrospective cohort study of the National Health and Nutrition Examination Survey 2007-2018. We estimated weighted sequential multivariable logistic regression models to predict odds of uncontrolled T2DM (HbA1c ≥ 8%) from racial and ethnic identity, adjusting for demographic, socioeconomic, and health indicators.
Results: Of 3649 individuals with T2DM who reported taking medication, 27.4% had uncontrolled T2DM (mean HgA1c 9.6%). Those with uncontrolled diabetes had a mean BMI of 33.8, age of 57.3, and most were non-Hispanic white (54%), followed by 17% non-Hispanic Black, and 20% Hispanic identity. In multivariable analyses, odds of uncontrolled T2DM among those with Black or Hispanic identities lessened, but persisted, after accounting for other indicators (Black OR 1.38, 97.5% CI: 1.04, 1.83; Hispanic OR 1.79, 97.5% CI 1.25, 2.57).
Conclusions: Racial and ethnic disparities in T2DM control persisted among individuals taking medication. Future research might focus on developmental and epigenetic pathways of disparate T2DM control across racially and ethnically minoritized populations.
Competing Interests: Conflict of Interest Dr. Anita T. Misra-Hebert reports grants or contracts with the following entities that are related to the content of this manuscript: Agency for Healthcare Research and Quality, National Heart Lung and Blood Institute, National Human Genome Research Institute, National Institute of Aging, Novo Nordisk, Inc., Merck Inc., and Boehringer Ingelheim Pharmaceuticals, Inc. No other authors report any potential conflict of interest.
(Copyright © 2024 Primary Care Diabetes Europe. Published by Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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