828 kHz retinal imaging with an 840 nm Fourier domain mode locked laser.

Autor:	Klufts M; Institute of Biomedical Optics, University of Lübeck, Lübeck 23562, Germany., Jiménez AM; School of Physical Sciences, University of Kent, Canterbury CT2 7NH, United Kingdom., Lotz S; Institute of Biomedical Optics, University of Lübeck, Lübeck 23562, Germany., Bashir MA; Institute of Biomedical Optics, University of Lübeck, Lübeck 23562, Germany., Pfeiffer T; Optores GmbH, Munich, 80339, Germany., Mlynek A; Optores GmbH, Munich, 80339, Germany., Wieser W; Optores GmbH, Munich, 80339, Germany., Chamorovskiy A; Superlum Diodes Ltd., Carrigtwohill, Cork T45 FC93, Ireland., Bradu A; School of Physical Sciences, University of Kent, Canterbury CT2 7NH, United Kingdom., Podoleanu A; School of Physical Sciences, University of Kent, Canterbury CT2 7NH, United Kingdom., Huber R; Institute of Biomedical Optics, University of Lübeck, Lübeck 23562, Germany.
Jazyk:	angličtina
Zdroj:	Biomedical optics express [Biomed Opt Express] 2023 Nov 28; Vol. 14 (12), pp. 6493-6508. Date of Electronic Publication: 2023 Nov 28 (Print Publication: 2023).
DOI:	10.1364/BOE.504302
Abstrakt:	This paper presents a Fourier domain mode locked (FDML) laser centered around 840 nm. It features a bidirectional sweep repetition rate of 828 kHz and a spectral bandwidth of 40 nm. An axial resolution of ∼9.9 µm in water and a 1.4 cm sensitivity roll-off are achieved. Utilizing a complex master-slave (CMS) recalibration method and due to a sufficiently high sensitivity of 84.6 dB, retinal layers of the human eye in-vivo can be resolved during optical coherence tomography (OCT) examination. The developed FDML laser enables acquisition rates of 3D-volumes with a size of 200 × 100 × 256 voxels in under 100 milliseconds. Detailed information on the FDML implementation, its challenging design tasks, and OCT images obtained with the laser are presented in this paper. Competing Interests: T. Pfeiffer: University of Lübeck (P), Optores GmbH (E); A. Mlynek: Optores GmbH (E); W. Wieser: Ludwig Maximilian University of Munich (P), Optores GmbH (I, E); A. Chamorovskiy: Superlum Ltd. (E); A. Bradu: University of Kent (P); A. Podoleanu: University of Kent (P); R. Huber: University of Lübeck (P), Ludwig Maximilian University of Munich (P), Optores GmbH (I, P, R), Optovue Inc. (I, R), Abott (I, R). (© 2023 Optica Publishing Group.)
Databáze:	MEDLINE
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