Diagnosis of intrahepatic cholangiocarcinoma with CEUS.

Autor: Gismondo Velardi G; Department of Radiology, Jazzolino Hospital, ASP Vibo Valentia, Vibo Valentia, Italy., Lico M; Department of Radiology, Jazzolino Hospital, ASP Vibo Valentia, Vibo Valentia, Italy., Teti A; Department of Radiology, Jazzolino Hospital, ASP Vibo Valentia, Vibo Valentia, Italy., Maccarone R; Department of Radiology, Jazzolino Hospital, ASP Vibo Valentia, Vibo Valentia, Italy., Casuscelli G; Department of Radiology, Jazzolino Hospital, ASP Vibo Valentia, Vibo Valentia, Italy., Militano L; Department of Radiology, Jazzolino Hospital, ASP Vibo Valentia, Vibo Valentia, Italy., Trecroci IV; Department of Radiology, Jazzolino Hospital, ASP Vibo Valentia, Vibo Valentia, Italy., Mendicino M; Department of Radiology, Giovanni Paolo II Hospital, ASP Catanzaro, Lamezia Terme, Italy., Parlati A; Department of Radiology, Giovanni Paolo II Hospital, ASP Catanzaro, Lamezia Terme, Italy., De Caridi A; Department of Radiology, Giovanni Paolo II Hospital, ASP Catanzaro, Lamezia Terme, Italy., Loria G; Department of Radiology, Giovanni Paolo II Hospital, ASP Catanzaro, Lamezia Terme, Italy., Loria S; Faculty of Medicine, UMG, Catanzaro, Italy., Loria S; Unicamillus International Medical University, Roma, Italy, Italy., Gambardella D; Department of Surgery, Giovanni Paolo II Hospital, ASP Catanzaro, Lamezia Terme, Italy., Tedesco M; Department of Surgery, Giovanni Paolo II Hospital, ASP Catanzaro, Lamezia Terme, Italy., Frosina F; General Medicine, Asp Reggio Calabria, Reggio Calabria, Italy., Falco P; Department of Pediatric Oncohematology, Grande Ospedale Metropolitano, Azienda Ospedaliera Bianchi Melacrino Morelli, Reggio Calabria, Italy., Loria F; Department of Radiology, Jazzolino Hospital, ASP Vibo Valentia, Vibo Valentia, Italy.
Jazyk: angličtina
Zdroj: Journal of ultrasonography [J Ultrason] 2024 Feb 27; Vol. 24 (96), pp. 20240005. Date of Electronic Publication: 2024 Feb 27 (Print Publication: 2024).
DOI: 10.15557/jou.2024.0005
Abstrakt: Intrahepatic cholangiocarcinoma (ICC) is a rare, heterogeneous, highly lethal tumor of the biliary tract. Due to the lack of effective treatments, an early identification of ICC is essential to achieve the best outcome in terms of therapy and prognosis aiming for a curative intent. ICC may arise on a normal liver or with an underlying liver disease, making the diagnosis more difficult and complex. Contrast-enhancement ultrasound (CEUS) is an accurate procedure able to detect ICC-specific contrast vascular pattern, and thus facilitating the correlation between radiological and histopathological findings with high specificity and sensitivity. CEUS has been shown to have a high diagnostic potential in the diagnosis of ICC thanks to the possibility of studying in real time the intralesional microcirculation and evaluating the precocity of the enhancement of the lesion during the arterial phase. All these features allow to differentiate the ICC from hepatocarcinoma (HCC) with high sensitivity and specificity. Furthermore, CEUS is a rapid, non-invasive, non-nephrotoxic or non-allergenic tool. The only limitations CEUS may have are related to the disease site and patient characteristics (obesity) and compliance, including the operator's experience. A clinical evaluation of the patient, together with tumor markers and biochemical tests assessment, to differentiate ICC from HCC are highly suggested.
Competing Interests: Conflicts of interest The authors do not report any financial or personal connections with other persons or organizations which might negatively affect the contents of this publication and/or claim authorship rights to this publication.
(© 2024 Giancarlo Gismondo Velardi et al., published by Sciendo.)
Databáze: MEDLINE
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