Transcranial magnetic stimulation therapy for central post-stroke pain: systematic review and meta-analysis.
| Autor: | Gurdiel-Álvarez F; International Doctoral School, Faculty of Health Sciences, Rey Juan Carlos University, Madrid, Spain.; Department of Physical Therapy, Occupational Therapy, Rehabilitation and Physical Medicine, Rey Juan Carlos University, Madrid, Spain.; Cognitive Neuroscience, Pain, and Rehabilitation Research Group (NECODOR), Faculty of Health Sciences, Rey Juan Carlos University, Madrid, Spain., Navarro-López V; Department of Physical Therapy, Occupational Therapy, Rehabilitation and Physical Medicine, Rey Juan Carlos University, Madrid, Spain., Varela-Rodríguez S; Department of Nursing and Physiotherapy, Faculty of Nursing and Physiotherapy, Instituto de Investigación Biomédica de Salamanca (IBSAL), Salamanca, Spain., Juárez-Vela R; Nursing Department, Faculty of Health Sciences, University of La Rioja, Research Group GRUPAC, Logroño, Spain., Cobos-Rincón A; Nursing Department, Faculty of Health Sciences, University of La Rioja, Research Group GRUPAC, Logroño, Spain., Sánchez-González JL; Department of Nursing and Physiotherapy, Faculty of Nursing and Physiotherapy, Instituto de Investigación Biomédica de Salamanca (IBSAL), Salamanca, Spain. |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | Frontiers in neuroscience [Front Neurosci] 2024 Feb 14; Vol. 18, pp. 1345128. Date of Electronic Publication: 2024 Feb 14 (Print Publication: 2024). |
| DOI: | 10.3389/fnins.2024.1345128 |
| Abstrakt: | Introduction: Although rare, central post-stroke pain remains one of the most refractory forms of neuropathic pain. It has been reported that repetitive transcranial magnetic stimulation (rTMS) may be effective in these cases of pain. Aim: The aim of this study was to investigate the efficacy of rTMS in patients with central post-stroke pain (CPSP). Methods: We included randomized controlled trials or Controlled Trials published until October 3rd, 2022, which studied the effect of rTMS compared to placebo in CPSP. We included studies of adult patients (>18 years) with a clinical diagnosis of stroke, in which the intervention consisted of the application of rTMS to treat CSP. Results: Nine studies were included in the qualitative analysis; 6 studies (4 RCT and 2 non-RCT), with 180 participants, were included in the quantitative analysis. A significant reduction in CPSP was found in favor of rTMS compared with sham, with a large effect size (SMD: -1.45; 95% CI: -1.87; -1.03; p < 0.001; I2: 58%). Conclusion: The findings of the present systematic review with meta-analysis suggest that there is low quality evidence for the effectiveness of rTMS in reducing CPSP. Systematic Review Registration: Identifier (CRD42022365655). Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The reviewer ER-A declared a past co-authorship with the author RJ-V to the handling editor. (Copyright © 2024 Gurdiel-Álvarez, Navarro-López, Varela-Rodríguez, Juárez-Vela, Cobos-Rincón and Sánchez-González.) |
| Databáze: | MEDLINE |
| Externí odkaz: |
|