Increasing temperature accelerates Ti-6Al-4V oxide degradation and selective dissolution: An Arrhenius-based analysis.
Autor: | Kurtz MA; Department of Bioengineering, Clemson University, Clemson, SC, USA; The Clemson University-Medical University of South Carolina Bioengineering Program, Charleston, SC, USA., Alaniz K; Department of Bioengineering, Clemson University, Clemson, SC, USA; The Clemson University-Medical University of South Carolina Bioengineering Program, Charleston, SC, USA., Taylor LM; Department of Bioengineering, Clemson University, Clemson, SC, USA; The Clemson University-Medical University of South Carolina Bioengineering Program, Charleston, SC, USA., Moreno-Reyes A; Department of Bioengineering, Clemson University, Clemson, SC, USA; The Clemson University-Medical University of South Carolina Bioengineering Program, Charleston, SC, USA., Gilbert JL; Department of Bioengineering, Clemson University, Clemson, SC, USA; The Clemson University-Medical University of South Carolina Bioengineering Program, Charleston, SC, USA. Electronic address: jlgilbe@clemson.edu. |
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Jazyk: | angličtina |
Zdroj: | Acta biomaterialia [Acta Biomater] 2024 Apr 01; Vol. 178, pp. 352-365. Date of Electronic Publication: 2024 Feb 27. |
DOI: | 10.1016/j.actbio.2024.02.028 |
Abstrakt: | Ti-6Al-4V selective dissolution occurs in vivo on orthopedic implants as the leading edge of a pitting corrosion attack. A gap persists in our fundamental understanding of selective dissolution and pre-clinical tests fail to reproduce this damage. While CoCrMo clinical use decreases, Ti-6Al-4V and the crevice geometries where corrosion can occur remain ubiquitous in implant design. Additionally, most additively manufactured devices cleared by the FDA use Ti-6Al-4V. Accelerated preclinical testing, therefore, would aid in the evaluation of new titanium devices and biomaterials. In this study, using temperature, we (1) developed an accelerated pre-clinical methodology to rapidly induce dissolution and (2) investigated the structure-property relationship between the dissolving surface and the oxide layer. We hypothesized that solution temperature and H Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests Dr. Jeremy Gilbert reports financial support was provided by Wyss Foundation. Dr. Jeremy Gilbert reports financial support was provided by DePuy Synthes. Dr. Jeremy Gilbert reports a relationship with Zimmer Biomet that includes: consulting or advisory. Dr. Jeremy Gilbert reports a relationship with Bausch and Lomb that includes: consulting or advisory. Dr. Jeremy Gilbert reports a relationship with Stryker Inc. that includes: consulting or advisory. Dr. Jeremy Gilbert reports a relationship with Corin/Omnilife Sciences and Naples Community Hospital that includes: consulting or advisory. Dr. Jeremy Gilbert reports a relationship with Smith and Nephew Inc that includes: consulting or advisory. Dr. Jeremy Gilbert reports a relationship with DePuy Synthes that includes: funding grants. Dr. Jeremy Gilbert reports a relationship with Bayer AG that includes: funding grants. Dr. Jeremy Gilbert reports a relationship with John Wiley & Sons Inc that includes: board membership. Dr. Jeremy Gilbert reports a relationship with Syracuse Bio-Materials Company LLC that includes: employment. Dr. Jeremy Gilbert reports a relationship with Society For Biomaterials that includes: board membership. (Copyright © 2024 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.) |
Databáze: | MEDLINE |
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