Long-term follow-up on patient-reported outcomes after supervised exercise training in individuals at risk of complications to type 2 diabetes.

Autor: Danielsen JH; Copenhagen University Hospital - Steno Diabetes Center Copenhagen, Herlev, Denmark. Electronic address: julie.hagstroem.danielsen.01@regionh.dk., Nielsen SG; Copenhagen University Hospital - Steno Diabetes Center Copenhagen, Herlev, Denmark. Electronic address: Susanne.groen.nielsen.01@regionh.dk., Varming AR; Copenhagen University Hospital - Steno Diabetes Center Copenhagen, Herlev, Denmark. Electronic address: Annemarie.varming@regionh.dk., Vilsbøll T; Copenhagen University Hospital - Steno Diabetes Center Copenhagen, Herlev, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. Electronic address: Tina.vilsboell.01@regionh.dk., Molsted S; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Clinical Research, Nordsjællands Hospital, Hillerød, Denmark. Electronic address: Stig.moelsted@regionh.dk.
Jazyk: angličtina
Zdroj: Diabetes & metabolic syndrome [Diabetes Metab Syndr] 2024 Feb; Vol. 18 (2), pp. 102953. Date of Electronic Publication: 2024 Feb 03.
DOI: 10.1016/j.dsx.2024.102953
Abstrakt: Aims: We investigated long-term changes of patient-reported outcomes after a supervised exercise intervention in individuals with type 2 diabetes (T2D).
Methods: In an intervention study without a control group, follow-up assessments were performed 12 months after initiating 12 weeks of physical exercise in individuals with T2D at intermediate or high risk of complications. Primary outcomes were health-related quality of life assessed with EQ-5D-5L, empowerment with Diabetes Empowerment Scale-Short Form, and self-reported physical activity with the Physical Activity Scale. Secondary outcomes were physical function (30-s chair-stand test) and working capacity (Aastrand or Graded Cycling Test).
Results: 153 participants completed follow-up (35% women, age (mean ± SD) 67 ± 11 years, body mass index 33.1 ± 5.9 kg/m 2 , glycated haemoglobin A1c 7.8 ± 3.7%). No changes were reported in health-related quality of life (index score p = 0.444, visual analogue scale p = 0.270), empowerment (p = 0.232), and moderate intensity physical activity (p = 0.917). Vigorous intensity physical activity decreased (mean (95% CI) -25.5 (-37.14; -13.94) min/day, p < 0.001). Physical function increased (p < 0.001) and working capacity decreased (Aastrand p = 0.002, Graded Cycling Test p = 0.039).
Conclusions: Health-related quality of life, empowerment, and self-reported moderate intensity physical activity time remained elevated at the long-term follow-up after a supervised exercise intervention.
Competing Interests: Declaration of competing interest Competing interests' statement: (even if the authors have no competing interests to declare). JHD, SGN, AV and SM have no competing interests to declare. TV has served on scientific advisory panels, been part of speaker's bureaus, served as a consultant to and/or received research support from Amgen, AstraZeneca, Boehringer Ingelheim, BMS, Eli Lilly, Gilead, GSK, Mundipharma, MSD/Merck, Novo Nordisk, Sanofi and Sun Pharmaceuticals.
(Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)
Databáze: MEDLINE
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