Waterhouse-Friderichsen syndrome, septic adrenal apoplexy.
| Autor: | Rijal R; University of Louisville School of Medicine, Louisville, KY, United States. Electronic address: rijalrishi@gmail.com., Kandel K; Matri Shishu Miteri Hospital, Gandaki Province, Nepal., Aryal BB; Department of Internal Medicine, Mount Sinai Hospital, Chicago, IL, United States. Electronic address: beingbarunaryal@gmail.com., Asija A; Division of Nephrology, Indiana University, Indianapolis, IN, United States. Electronic address: asijaankush@gmail.com., Shrestha DB; Department of Internal Medicine, Mount Sinai Hospital, Chicago, IL, United States. Electronic address: medhan75@gmail.com., Sedhai YR; Division of Pulmonary Disease and Critical Care Medicine, University of Kentucky College of Medicine, Bowling Green, KY, United States. Electronic address: dr.sedhai@gmail.com. |
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| Jazyk: | angličtina |
| Zdroj: | Vitamins and hormones [Vitam Horm] 2024; Vol. 124, pp. 449-461. Date of Electronic Publication: 2023 Nov 08. |
| DOI: | 10.1016/bs.vh.2023.06.001 |
| Abstrakt: | Waterhouse-Friderichsen syndrome is a rare but potentially fatal disorder of the adrenal gland characterized by bilateral adrenal hemorrhage. It is classically a result of meningococcal sepsis and presents acutely with features of shock, petechial rashes, abdominal pain, and non-specific symptoms such as headache, fatigue, and vomiting. Treatment consists of fluid resuscitation, corticosteroid replacement, and possibly surgery. The prognosis is poor despite treatment. This chapter will review the etiology, pathogenesis, clinical features, and management of the disease. (Copyright © 2024. Published by Elsevier Inc.) |
| Databáze: | MEDLINE |
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