How complicated can be a case with immune thrombocytopenic purpura?: postsplenectomy arterial thrombosis.

Autor: Kaya AD; Ibrahim Cecen University, Agri Training and Research Hospital, Department of Cardiovascular Surgery., Tekin O; Ibrahim Cecen University, Agri Training and Research Hospital, Department of General Surgery., Colak Y; Ibrahim Cecen University, Agri Training and Research Hospital, Department of Hematology, Agri, Turkey., Serin I; Ibrahim Cecen University, Agri Training and Research Hospital, Department of Hematology, Agri, Turkey.
Jazyk: angličtina
Zdroj: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis [Blood Coagul Fibrinolysis] 2024 Jun 01; Vol. 35 (4), pp. 209-213. Date of Electronic Publication: 2024 Feb 21.
DOI: 10.1097/MBC.0000000000001290
Abstrakt: Arterial thrombus associated with the surgery can be seen in postsplenectomy cases, but there is no clear data in patients diagnosed with immune thrombocytopenic purpura (ITP). A 52-year-old female patient was admitted to the emergency department due to ecchymotic skin changes. Her initial platelet count was 6000/mm 3 ; after two courses of high dose-dexamethasone, intravenous immunoglobulin and rituximab, splenectomy was planned for the patient whose platelet count was again <40 000/mm 3 . She presented to the emergency department with complaints of pain and pallor in the right arm in the second week of follow-up. There was a mural thrombus that caused approximately 50% stenosis in the lumen at the division site in the aortic arch, proximal of the right subclavian artery. The patient's clinic was found to be associated with the presence of an aberrant right subclavian artery and postoperative thrombocytosis/inflammation after elimination other prothrombotic conditions.
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Databáze: MEDLINE