Time to treatment disparities in gastric cancer patients in the United States of America: a comprehensive retrospective analysis.

Autor:	Sharan S; Department of Surgery, Government Medical College and Hospital, Chandigarh, India., Bansal S; Department of Surgery, Government Medical College and Hospital, Chandigarh, India., Manaise HK; Department of Surgery, Government Medical College and Hospital, Chandigarh, India., Jimenez PB; Department of Surgery, University of Puerto Rico School of Medicine, San Juan, Puerto Rico., Raikot SR; Department of Surgery, Mayo Clinic, Rochester, MN, United States., Ahmed SH; Department of Surgery, Dow University of Health Sciences, Karachi, Pakistan., Popp R; Department of Surgery, University of Florida College of Medicine, Gainesville, FL, United States., Popp K; Department of Surgery, Florida State University, Tallahassee, FL, United States., Sukniam K; Department of Surgery, Duke University Medical Center, Durham, NC, United States., Kowkabany G; Department of Surgery, University of Alabama, Tuscaloosa, AL, United States., Mubarak F; Department of Surgery, Aga Khan University, Karachi, Pakistan., Gabriel E; Department of General Surgery, Mayo Clinic Florida, Jacksonville, FL, United States.
Jazyk:	angličtina
Zdroj:	Frontiers in oncology [Front Oncol] 2024 Feb 09; Vol. 14, pp. 1292793. Date of Electronic Publication: 2024 Feb 09 (Print Publication: 2024).
DOI:	10.3389/fonc.2024.1292793
Abstrakt:	Introduction: Gastric cancer ranks as the 5th most prevalent cancer and the 4th leading cause of cancer-related deaths worldwide. Various treatment modalities, including surgical resection, chemotherapy, and radiotherapy, are available for gastric cancer patients. However, disparities related to age, sex, race, socioeconomic factors, insurance status, and demographic factors often lead to delayed time to treatment. Methods: In this retrospective study, conducted between 2004 and 2019, we utilized data from the National Cancer Database (NCDB) to investigate the factors contributing to disparities in the time to first treatment, surgery, chemotherapy, and radiotherapy among gastric cancer patients. Our analysis incorporated several variables, and statistical analysis was conducted to provide valuable insights into these disparities. Results: We observed notable disparities in the timing of treatment for various demographic groups, including age, sex, race, insurance status, geographic location, and facility type. These disparities include longer time to treatment in males (32.67 vs 30.75), Native Americans (35.10 vs 31.09 in Asians), low-income patients (32 vs 31.15), patients getting treatment in an academic setting (36.11 vs 29.61 in community setting), significantly longer time to chemotherapy in 70+ age group (51.13 vs 40.38 in <40 y age group), black race (55.81 vs 47.05 in whites), low income people (49.64 vs 46.74), significantly longer time to radiotherapy in females (101.61 vs 79.75), blacks and Asians (109.68 and 113.96 respectively vs 92.68 in Native Americans) etc. There are various other disparities in time to surgery, chemotherapy, and radiotherapy. Conclusions: Understanding these disparities is crucial in developing targeted strategies to improve timely access to appropriate treatments and enhance outcomes for gastric cancer patients. Future research with updated data and prospective study designs can provide a more comprehensive understanding of the factors influencing patient outcomes in gastric cancer. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that author EG was an associate editor and they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision. (Copyright © 2024 Sharan, Bansal, Manaise, Jimenez, Raikot, Ahmed, Popp, Popp, Sukniam, Kowkabany, Mubarak and Gabriel.)
Databáze:	MEDLINE
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