Five degrees-of-freedom mechanical arm with remote center of motion (RCM) device for volumetric optical coherence tomography (OCT) retinal imaging.
| Autor: | Ahronovich E; Department of Mechanical Engineering, Vanderbilt University, Nashville, TN, USA., Shen JH; Vanderbilt Eye Institute, Vanderbilt University 2311 Pierce Avenue Nashville, TN 37232, USA., Vadakkan TJ; Vanderbilt University Cell Imaging Shared Resources (CISR), Nashville, TN, USA., Prasad R; Vanderbilt Eye Institute, Vanderbilt University 2311 Pierce Avenue Nashville, TN 37232, USA., Joos KM; Vanderbilt Eye Institute, Vanderbilt University 2311 Pierce Avenue Nashville, TN 37232, USA.; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA., Simaan N; Department of Mechanical Engineering, Vanderbilt University, Nashville, TN, USA.; Department of Computer Science, Vanderbilt University, Nashville, TN, USA.; Department of Otolaryngology-Head & Neck Surgery, Vanderbilt University, Nashville, TN, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Biomedical optics express [Biomed Opt Express] 2024 Jan 29; Vol. 15 (2), pp. 1150-1162. Date of Electronic Publication: 2024 Jan 29 (Print Publication: 2024). |
| DOI: | 10.1364/BOE.505294 |
| Abstrakt: | Handheld optical coherence tomography (HH-OCT) is gaining popularity for diagnosing retinal diseases in neonates (e.g. retinopathy of prematurity). Diagnosis accuracy is degraded by hand tremor and patient motion when using commercially available handheld retinal OCT probes. This work presents a low-cost arm designed to address ergonomic challenges of holding a commercial OCT probe and alleviating hand tremor. Experiments with a phantom eye show enhanced geometric uniformity and volumetric accuracy when obtaining OCT scans with our device compared to handheld imaging approaches. An in-vivo porcine volumetric image was also obtained with the mechanical arm demonstrating clinical deployability. Competing Interests: The authors declare no conflicts of interest. (© 2024 Optica Publishing Group.) |
| Databáze: | MEDLINE |
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