Phenotyping cardiopulmonary exercise testing measures in heart failure with reduced ejection fraction: A comparison between Italy and Brazil.

Autor: Goulart CDL; Cardiopulmonary Physiotherapy Laboratory, Physiotherapy Department, Federal University of Sao Carlos, UFSCar, Rodovia Washington Luis, KM 235, Monjolinho, CEP: 13565-905, Sao Carlos, SP 13565-905, Brazil., Agostoni P; Centro Cardiologico Monzino, IRCCS, Via Parea 4, Milan 20138, Italy; Department of Clinical Sciences and Community Health, Cardiovascular Section, University of Milano, Milano, Italy., Salvioni E; Centro Cardiologico Monzino, IRCCS, Via Parea 4, Milan 20138, Italy., Silva RN; Cardiopulmonary Physiotherapy Laboratory, Physiotherapy Department, Federal University of Sao Carlos, UFSCar, Rodovia Washington Luis, KM 235, Monjolinho, CEP: 13565-905, Sao Carlos, SP 13565-905, Brazil., Bassi-Dibai D; Postgraduate Program in Management in Health Programs and Services, Universidade CEUMA, São Luís, MA, Brazil., Roscani MG; Cardiology and Exercise Research Center Laboratory, Department of Medicine, Federal University of São Carlos, SP, Brazil., Arena R; Department of Physical Therapy, College of Applied Health Sciences, University of Illinois Chicago, Chicago, IL, United States., Myers J; Veterans Affairs Palo Alto Health Care System and Stanford University, Palo Alto CA, United States., Borghi-Silva A; Cardiopulmonary Physiotherapy Laboratory, Physiotherapy Department, Federal University of Sao Carlos, UFSCar, Rodovia Washington Luis, KM 235, Monjolinho, CEP: 13565-905, Sao Carlos, SP 13565-905, Brazil. Electronic address: audrey@ufscar.br.
Jazyk: angličtina
Zdroj: Heart & lung : the journal of critical care [Heart Lung] 2024 May-Jun; Vol. 65, pp. 54-58. Date of Electronic Publication: 2024 Feb 24.
DOI: 10.1016/j.hrtlng.2024.02.002
Abstrakt: Background: While patients with heart failure (HF) with reduced left ventricular ejection fraction (HFrEF) constitutes a global health crisis the incidence, prevalence and prognosis of the disease may differ depending on the continent and country.
Objective: To profile, analyze and compare cardiopulmonary exercise testing (CPET) data of patients with HFrEF between Italian and Brazilian cohorts.
Methods: In this observational study, a total of 630 patients with clinical and functional diagnosis of HFrEF (315 patients from Brazil and 315 patients from Italy) performed CPET.
Results: Although Brazilian patients were slightly younger (Brazil 60±10 vs Italy 64±11 p<0.001) with a better peak oxygen consumption (V̇O 2 ), circulatory power and left ventricular ejection fraction (LVEF) (p<0.01), ventilatory inefficiency and oscillation ventilation was higher when compared to the Italian cohort. When stratifying patients with LVEF≤30 % and age≥60 years, Brazilian patients presented worse ventilatory efficiency, and lower peak V̇O 2 compared to the Italian cohort.
Conclusion: Patients with HFrEF from Brazil exhibited higher ventilatory inefficiency and a greater prevalence of oscillatory ventilation during CPET compared to patients with the same diagnosis from Italy.
Competing Interests: Declaration of competing interest No potential conflict of interest was reported by the authors.
(Copyright © 2024. Published by Elsevier Inc.)
Databáze: MEDLINE
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