| Autor: |
Mathar CE; Department of Anaesthesia and Intensive Care, Copenhagen University Hospital-Bispebjerg and Frederiksberg, DK-2400 Copenhagen, Denmark., Haahr-Raunkjær C; Center for Cancer and Organ Diseases, Department of Anaesthesia, Copenhagen University Hospital-Rigshospitalet, DK-2100 Copenhagen, Denmark., Elvekjær M; Department of Anaesthesia and Intensive Care, Copenhagen University Hospital-Bispebjerg and Frederiksberg, DK-2400 Copenhagen, Denmark., Gu Y; Department of Health Technology, Technical University of Denmark, DK-2800 Lyngby, Denmark., Holm CP; Department of Respiratory Medicine, Copenhagen University Hospital-Bispebjerg and Frederiksberg, DK-2400 Copenhagen, Denmark., Achiam MP; Center for Cancer and Organ Disease, Department of Surgical Gastroenterology, Copenhagen University Hospital-Rigshospitalet, DK-2100 Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, DK-2100 Copenhagen, Denmark., Jorgensen LN; Department of Clinical Medicine, University of Copenhagen, DK-2100 Copenhagen, Denmark.; Digestive Disease Center, Copenhagen University Hospital-Bispebjerg and Frederiksberg, DK-2400 Copenhagen, Denmark., Aasvang EK; Center for Cancer and Organ Diseases, Department of Anaesthesia, Copenhagen University Hospital-Rigshospitalet, DK-2100 Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, DK-2100 Copenhagen, Denmark., Meyhoff CS; Department of Anaesthesia and Intensive Care, Copenhagen University Hospital-Bispebjerg and Frederiksberg, DK-2400 Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, DK-2100 Copenhagen, Denmark. |
| Abstrakt: |
The monitoring of oxygen therapy when patients are admitted to medical and surgical wards could be important because exposure to excessive oxygen administration (EOA) may have fatal consequences. We aimed to investigate the association between EOA, monitored by wireless pulse oximeter, and nonfatal serious adverse events (SAEs) and mortality within 30 days. We included patients in the Capital Region of Copenhagen between 2017 and 2018. Patients were hospitalized due to acute exacerbation of chronic obstructive pulmonary disease (AECOPD) or after major elective abdominal cancer surgery, and all were treated with oxygen supply. Patients were divided into groups by their exposure to EOA: no exposure, exposure for 1-59 min or exposure over 60 min. The primary outcome was SAEs or mortality within 30 days. We retrieved data from 567 patients for a total of 43,833 h, of whom, 63% were not exposed to EOA, 26% had EOA for 1-59 min and 11% had EOA for ≥60 min. Nonfatal SAEs or mortality within 30 days developed in 24%, 12% and 22%, respectively, and the adjusted odds ratio for this was 0.98 (95% CI, 0.96-1.01) for every 10 min. increase in EOA, without any subgroup effects. In conclusion, we did not observe higher frequencies of nonfatal SAEs or mortality within 30 days in patients exposed to excessive oxygen administration. |
