| Autor: |
Guedes PEB; Postgraduate Program in Animal Science, State University of Santa Cruz (UESC), Ilhéus 45662-900, BA, Brazil., Pinto TM; Postgraduate Program in Animal Science, State University of Santa Cruz (UESC), Ilhéus 45662-900, BA, Brazil., Corrêa JMX; Postgraduate Program in Animal Science, State University of Santa Cruz (UESC), Ilhéus 45662-900, BA, Brazil., Niella RV; Postgraduate Program in Animal Science, State University of Santa Cruz (UESC), Ilhéus 45662-900, BA, Brazil., Dos Anjos CM; Postgraduate Program in Animal Science, State University of Santa Cruz (UESC), Ilhéus 45662-900, BA, Brazil., de Oliveira JNS; Postgraduate Program in Animal Science, State University of Santa Cruz (UESC), Ilhéus 45662-900, BA, Brazil., Marques CSDC; Postgraduate Program in Animal Science, State University of Santa Cruz (UESC), Ilhéus 45662-900, BA, Brazil., de Souza SS; Postgraduate Program in Animal Science, State University of Santa Cruz (UESC), Ilhéus 45662-900, BA, Brazil., da Silva EB; Department of Agricultural and Environmental Sciences, State University of Santa Cruz (UESC), Ilhéus 45662-900, BA, Brazil., de Lavor MSL; Department of Agricultural and Environmental Sciences, State University of Santa Cruz (UESC), Ilhéus 45662-900, BA, Brazil. |
| Abstrakt: |
This study aimed to evaluate the effect of the preemptive administration of amantadine on postoperative analgesia in cats undergoing ovariohysterectomy and its influence on the physiological parameters. Twenty healthy domestic cats scheduled to undergo ovariohysterectomy at the Santa Cruz State University, Ilhéus, were divided into two groups: the control group (Group C; n = 10) and the amantadine group (Group A; n = 10). The cats in Group C received placebo capsules 30 min prior to the standard anesthetic protocol, whereas those in Group A received 5 mg/kg of amantadine orally 30 min prior to the standard anesthetic protocol. Postoperative pain was assessed using the visual analog scale and the UNESP-Botucatu multidimensional scale for the evaluation of postoperative pain in cats. The administration of amantadine had no effect on the physiological parameters evaluated. The pain scores in Group A were lower than those in Group C, indicating that the frequency of rescue analgesic administration cats in Group A was lower. That way, preemptive oral administration of amantadine at a dose of 5 mg/kg was effective at controlling postoperative pain in cats undergoing ovariohysterectomy. Moreover, no adverse effects or alterations in the physiological patterns were observed in the treated animals. |
