Toxicity of representative organophosphate, organochlorine, phenylurea, dinitroaniline, carbamate, and viologen pesticides to the growth and survival of H. vulgaris, L. minor, and C. elegans.

Autor: Rivenbark KJ; Interdisciplinary Faculty of Toxicology, Texas A&M University, College Station, TX, USA.; Department of Veterinary Physiology and Pharmacology, School of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, USA., Nikkhah H; Department of Chemical and Biomolecular Engineering, University of Connecticut, Storrs, CT, USA.; Center for Clean Energy Engineering, University of Connecticut, Storrs, CT, USA., Wang M; Interdisciplinary Faculty of Toxicology, Texas A&M University, College Station, TX, USA.; Department of Veterinary Physiology and Pharmacology, School of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, USA., Beykal B; Department of Chemical and Biomolecular Engineering, University of Connecticut, Storrs, CT, USA.; Center for Clean Energy Engineering, University of Connecticut, Storrs, CT, USA., Phillips TD; Interdisciplinary Faculty of Toxicology, Texas A&M University, College Station, TX, USA. tphillips@cvm.tamu.edu.; Department of Veterinary Physiology and Pharmacology, School of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, USA. tphillips@cvm.tamu.edu.
Jazyk: angličtina
Zdroj: Environmental science and pollution research international [Environ Sci Pollut Res Int] 2024 Mar; Vol. 31 (14), pp. 21781-21796. Date of Electronic Publication: 2024 Feb 24.
DOI: 10.1007/s11356-024-32444-5
Abstrakt: Pesticides are commonly found in the environment and pose a risk to target and non-target species; therefore, employing a set of bioassays to rapidly assess the toxicity of these chemicals to diverse species is crucial. The toxicity of nine individual pesticides from organophosphate, organochlorine, phenylurea, dinitroaniline, carbamate, and viologen chemical classes and a mixture of all the compounds were tested in three bioassays (Hydra vulgaris, Lemna minor, and Caenorhabditis elegans) that represent plant, aquatic, and soil-dwelling species, respectively. Multiple endpoints related to growth and survival were measured for each model, and EC 10 and EC 50 values were derived for each endpoint to identify sensitivity patterns according to chemical classes and target organisms. L. minor had the lowest EC 10 and EC 50 values for seven and five of the individual pesticides, respectively. L. minor was also one to two orders of magnitude more sensitive to the mixture compared to H. vulgaris and C. elegans, where EC 50 values were calculated to be 0.00042, 0.0014, and 0.038 mM, respectively. H. vulgaris was the most sensitive species to the remaining individual pesticides, and C. elegans consistently ranked the least sensitive to all tested compounds. When comparing the EC 50 values across all pesticides, the endpoints of L. minor were correlated with each other while the endpoints measured in H. vulgaris and C. elegans were clustered together. While there was no apparent relationship between the chemical class of pesticide and toxicity, the compounds were more closely clustered based on target organisms (herbicide vs insecticide). The results of this study demonstrate that the combination of these plant, soil, and aquatic specie can serve as representative indicators of pesticide pollution in environmental samples.
(© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
Databáze: MEDLINE
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