Directional epistasis is common in morphological divergence.
| Autor: | Bourg S; Department of Biology, Centre for Biodiversity Dynamics, Norwegian University of Science and Technology (NTNU), Trondheim, Norway., Bolstad GH; Norwegian Institute for Nature Research (NINA), Trondheim, Norway., Griffin DV; Department of Biological Science, Florida State University, Tallahassee, FL, United States., Pélabon C; Department of Biology, Centre for Biodiversity Dynamics, Norwegian University of Science and Technology (NTNU), Trondheim, Norway., Hansen TF; Department of Biology, Centre for Ecological and Evolutionary Synthesis, University of Oslo, Oslo, Norway. |
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| Jazyk: | angličtina |
| Zdroj: | Evolution; international journal of organic evolution [Evolution] 2024 May 01; Vol. 78 (5), pp. 934-950. |
| DOI: | 10.1093/evolut/qpae029 |
| Abstrakt: | Epistasis is often portrayed as unimportant in evolution. While random patterns of epistasis may have limited effects on the response to selection, systematic directional epistasis can have substantial effects on evolutionary dynamics. Directional epistasis occurs when allele substitutions that change a trait also modify the effects of allele substitution at other loci in a systematic direction. In this case, trait evolution may induce correlated changes in allelic effects and additive genetic variance (evolvability) that modify further evolution. Although theory thus suggests a potentially important role for directional epistasis in evolution, we still lack empirical evidence about its prevalence and magnitude. Using a new framework to estimate systematic patterns of epistasis from line-crosses experiments, we quantify its effects on 197 size-related traits from diverging natural populations in 24 animal and 17 plant species. We show that directional epistasis is common and tends to become stronger with increasing morphological divergence. In animals, most traits displayed negative directionality toward larger size, suggesting that epistatic constraints reducing evolvability toward larger size. Dominance was also common but did not systematically alter the effects of epistasis. (© The Author(s) 2024. Published by Oxford University Press on behalf of The Society for the Study of Evolution (SSE).) |
| Databáze: | MEDLINE |
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