| Autor: |
Di Bella P; Unit of Child Neurology and Psychiatry, 'G. Martino' University Hospital, 98125 Messina, Italy., Attardi AG; Unit of Child Neurology and Psychiatry, 'G. Martino' University Hospital, 98125 Messina, Italy., Butera A; Unit of Child Neurology and Psychiatry, 'G. Martino' University Hospital, 98125 Messina, Italy., Mancini A; Unit of Child Neurology and Psychiatry, 'G. Martino' University Hospital, 98125 Messina, Italy., Calabrò N; Unit of Child Neurology and Psychiatry, 'G. Martino' University Hospital, 98125 Messina, Italy., Lo Re EG; Unit of Child Neurology and Psychiatry, 'G. Martino' University Hospital, 98125 Messina, Italy., Trimarchi G; SIR-Faculty of Medicine and Surgery, University of Messina, 98125 Messina, Italy., Nicotera AG; Unit of Child Neurology and Psychiatry, 'G. Martino' University Hospital, 98125 Messina, Italy., Di Rosa G; Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, 98125 Messina, Italy., Giudice DL; Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, 98125 Messina, Italy. |
| Abstrakt: |
The post-COVID-19 condition is defined by the World Health Organization as the persistence of symptoms or development of new symptoms three months after the initial SARS-CoV-2 infection, lasting for at least two months without a clear explanation. Neuropsychiatric disorders associated with this condition include asthenia, memory and concentration problems, and sleep disturbances. Our study aims to investigate sleep patterns following SARS-CoV-2 infection using EEG findings and a sleep quality questionnaire completed by parents (Sleep Disturbance Scale for Children-SDSC). Notably, our investigation is based on a convenience sample. The patients in our sample, aged 1 to 14 years, are not currently taking any medications; rather, they are undergoing follow-up assessments at the Child Neuropsychiatry department of the University Hospital of Messina for neurodevelopmental evaluations. Specifically, we are analyzing amplitude and power spectrum data in the first five minutes of NREM2 sleep, calculated from EEG recordings obtained via bipolar leads within three months after the onset of the disease. These results will be compared with controls performed on the same subjects in the six months preceding the infection. The focus of the study was sleep spindles, which are generated by the thalamocortical systems and play a role in sleep modulation, memory, and learning. Preliminary analysis suggests a predominant increase in the slow component of the spindles in the right-frontal lead. |
