Small-Diameter Blood Vessel Substitutes: Biomimetic Approaches to Improve Patency.

Autor: Behr JM; SMD Swiss Medical Devices AG, 8222 Beringen, Switzerland., Wong YS; Biomedical Engineering, School of Engineering, Temasek Polytechnic, Singapore 529757, Singapore., Venkatraman S; Materials Science and Engineering, National University of Singapore, Singapore 117575, Singapore.; iHealthTech, National University of Singapore, Singapore 117599, Singapore.
Jazyk: angličtina
Zdroj: Biomimetics (Basel, Switzerland) [Biomimetics (Basel)] 2024 Feb 07; Vol. 9 (2). Date of Electronic Publication: 2024 Feb 07.
DOI: 10.3390/biomimetics9020097
Abstrakt: Small-dimeter blood vessels (<6 mm) are required in coronary bypass and peripheral bypass surgery to circumvent blocked arteries. However, they have poor patency rates due to thrombus formation, intimal hyperplasia at the distal anastomosis, and compliance mismatch between the native artery and the graft. This review covers the state-of-the-art technologies for improving graft patency with a focus on reducing compliance mismatch between the prosthesis and the native artery. The focus of this article is on biomimetic design strategies to match the compliance over a wide pressure range.
Databáze: MEDLINE
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