Biomarkers for the diagnosis and monitoring of nitrous oxide intoxication: objectives and methodology of the SFBC Working Group.

Autor: Denimal D; Department of Clinical Biochemistry, Dijon Bourgogne University Hospital & INSERM UMR 1231, Center for Translational and Molecular Medicine, Dijon, France., Badiou S; Department of Biochemistry, University Hospital of Montpellier & PhyMedExp, University of Montpellier, INSERM, CNRS, Montpellier, France., Blin J; Department of Biochemistry, University Hospital of Nantes & INSERM, IMAD, Nantes, France., Bonnan M; Department of Neurology, Hospital of Saint-Denis, Saint-Denis, France., Boullier A; Department of Biochemistry, Amiens-Picardie University Hospital & MP3CV-UR7517, CURS-University of Picardie Jules Verne, Amiens, France., Chauvin A; Department of Emergency, Lariboisiere Hospital, Assistance Publique-Hôpitaux de Paris & Inserm U942 MASCOT, University of Paris, Paris, France., Dupont A; Department of Hematology and Transfusion, University Hospital of Lille, Lille, France., Diesnis R; Department of Emergency, Hospital of Roubaix, Roubaix, France., Dupré T; Department of Biochemistry, Bichat Hospital, Assistance Publique-Hôpitaux de Paris & Inserm U1149, University of Paris, Paris, France., Fabresse N; Department of Pharmacokinetics and Toxicology, La Timone University Hospital, Marseille, France., Gernez É; Department of Hormonology, Metabolism, Nutrition and Oncology, University Hospital of Lille, Lille, France., Imbard A; Department of Biochemistry, Assistance Publique-Hôpitaux de Paris & Paris Saclay University, Paris, France., Kim I; Department of Hormonology, Metabolism, Nutrition and Oncology, University Hospital of Lille, Lille, France., Mondesert É; Department of Biochemistry, University Hospital of Montpellier, Montpellier, France., Niguet JP; Department of Neurology, Groupement des Hôpitaux de l'Institut Catholique de Lille, Catholic University of Lille, Lille, France., Parant F; Department of Biology, Lyon-Sud Hospital, University Hospital of Lyon, Pierre-Bénite, France., Redonnet-Vernhet I; Department of Biochemistry, Pellegrin Hospital, University Hospital of Bordeaux & Inserm U1211, University of Bordeaux, France., Trillot N; Department of Hematology and Transfusion, University Hospital of Lille, Lille, France., Grzych G; Department of Hormonology, Metabolism, Nutrition and Oncology, University Hospital of Lille, Lille, France.
Jazyk: angličtina
Zdroj: Annales de biologie clinique [Ann Biol Clin (Paris)] 2024 Feb 24; Vol. 81 (6), pp. 585-590.
DOI: 10.1684/abc.2023.1858
Abstrakt: The recreational use of nitrous oxide (N2O) is an emerging public health issue. Chronic N2O abuse may result in various clinical symptoms, encompassing neurological, psychiatric and cardiovascular outcomes. Despite the difficulties for the laboratory investigation of N2O intoxication, there is currently no guidelines in France to help both clinicians and biologists use appropriate biomarkers for the diagnosis and monitoring of patients with clinical symptoms potentially related to N2O intoxication. A multi-disciplinary Working Group, carried out under the auspices of the French Society of Clinical Biology (SFBC) and in collaboration with the French Societies of Emergency Medicine (SFMU), Analytical Toxicology (SFTA), Hemostasis and Thrombosis (SFTH), Vitamins and Biofactors (SFVB), and the French Federation of Neurology (FFN), was recently implemented to elaborate practical guidelines. The methodology of the Working Group is based on the critical analysis of the literature, and raising concerns and objectives are grouped into five working packages. The present manuscript primarily aims to expound upon the methodology and objectives of the ongoing SFBC Working Group on N2O.
Databáze: MEDLINE