Onyx®, A New Tool for Intraoperative Localization of Liver Lesions.

Autor:	Rubio-García JJ; Servicio de Cirugía General y Aparato Digestivo, Hospital General Universitario de Alicante, Alicante, Spain.; Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIAL), Alicante, Spain., Mantilla Pinilla AJ; Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIAL), Alicante, Spain.; Servicio de Radiodiagnóstico y Radiología Intervencionista, Hospital General Universitario de Alicante, Alicante, Spain., Gil Sánchez S; Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIAL), Alicante, Spain.; Servicio de Radiodiagnóstico y Radiología Intervencionista, Hospital General Universitario de Alicante, Alicante, Spain., Villodre Tudela C; Servicio de Cirugía General y Aparato Digestivo, Hospital General Universitario de Alicante, Alicante, Spain.; Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIAL), Alicante, Spain., Alcázar López C; Servicio de Cirugía General y Aparato Digestivo, Hospital General Universitario de Alicante, Alicante, Spain.; Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIAL), Alicante, Spain., Melgar Requena P; Servicio de Cirugía General y Aparato Digestivo, Hospital General Universitario de Alicante, Alicante, Spain.; Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIAL), Alicante, Spain., Rodríguez Laiz G; Servicio de Cirugía General y Aparato Digestivo, Hospital General Universitario de Alicante, Alicante, Spain.; Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIAL), Alicante, Spain., Irurzun López J; Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIAL), Alicante, Spain.; Servicio de Radiodiagnóstico y Radiología Intervencionista, Hospital General Universitario de Alicante, Alicante, Spain., Ramia-Ángel JM; Servicio de Cirugía General y Aparato Digestivo, Hospital General Universitario de Alicante, Alicante, Spain.; Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIAL), Alicante, Spain.
Jazyk:	angličtina
Zdroj:	Surgical innovation [Surg Innov] 2024 Apr; Vol. 31 (2), pp. 220-223. Date of Electronic Publication: 2024 Feb 22.
DOI:	10.1177/15533506241236732
Abstrakt:	Background: Precise preoperative localization of liver tumors facilitates successful surgical procedures, Intraoperative ultrasonography is a sensitive imaging modality. However, the presence of small non-palpable isoechoic intraparenchymal lesions may be challenging intraoperatively. Methodology and Material Description: Onyx® is a non-adhesive liquid agent comprised of ethylene-vinyl alcohol usually used dissolved in dimethyl-sulfoxide and suspended micronized tantalum powder to provide contrast for visualization under fluoroscopy and ultrasonography and a macroscopic black shape. This embolization material has been increasingly used for the embolization of intracranial arteriovenous malformations. We present the novel application of Onyx® on liver surgery. Current Status: We present the case of a female, 55 years-old, whose medical history revealed an elective sigmoidectomy (pT3N1a). After 17 months of follow up, by PET-CT scan, the patient was diagnosed of a small intraparenchymal hypo-attenuated 13 mm tumor located at segment V consistent with metachronous colorectal liver metastasis. Open metastasectomy was performed, ultrasonography-guided Onyx® infusion was delivered the day after, intraoperative ultrasonography showed a palpable hyperechoic material with a posterior acoustic shadowing artifact around the lesion. Onyx® is a promising new tool, without any previous application on liver surgery, feasible with advantages in small not palpable intraparenchymal liver lesions. Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Databáze:	MEDLINE
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