Socioeconomic Deprivation and the Risk of Sight-Threatening Diabetic Retinopathy: A Population-Based Cohort Study in the U.K.

Autor:	Tan L; Institute of Applied Health Research, University of Birmingham, Birmingham, U.K., Wang J; Institute of Applied Health Research, University of Birmingham, Birmingham, U.K., Han J; Institute of Applied Health Research, University of Birmingham, Birmingham, U.K., Sainsbury C; Institute of Applied Health Research, University of Birmingham, Birmingham, U.K., Denniston AK; Academic Unit of Ophthalmology, Institute of Inflammation and Ageing, University of Birmingham, Birmingham, U.K.; National Institute for Health Research Birmingham Biomedical Research Centre, Birmingham, U.K., Crowe FL; Institute of Applied Health Research, University of Birmingham, Birmingham, U.K., Toulis KA; Institute of Applied Health Research, University of Birmingham, Birmingham, U.K., Karamat MA; Diabetes and Endocrinology Specialist Training Committee, Health Education West Midlands, Birmingham, U.K., Yao M; Department of General Practice, Peking University First Hospital, Beijing, China., Nirantharakumar K; Institute of Applied Health Research, University of Birmingham, Birmingham, U.K.
Jazyk:	angličtina
Zdroj:	Diabetes care [Diabetes Care] 2024 May 01; Vol. 47 (5), pp. 844-848.
DOI:	10.2337/dc23-1626
Abstrakt:	Objective: To evaluate the associations between socioeconomic deprivation and sight-threatening diabetic retinopathy (STDR) in individuals with type 1 diabetes (T1D) and type 2 diabetes (T2D). Research Design and Methods: Data from 175,628 individuals with diabetes in the Health Improvement Network were used to assess the risk of STDR across Townsend Deprivation Index quantiles using Cox proportional hazard regression. Results: Among individuals with T1D, the risk of STDR was three times higher (adjusted hazard ratio [aHR] 2.67, 95% CI 1.05-7.78) in the most deprived quintile compared with the least deprived quintile. In T2D, the most deprived quintile had a 28% higher risk (aHR 1.28; 95% CI 1.15-1.43) than the least deprived quintile. Conclusions: Increasing socioeconomic deprivation is associated with a higher risk of developing STDR in people with diabetes. This underscores persistent health disparities linked to poverty, even within a country offering free universal health care. Further research is needed to address health equity concerns in socioeconomically deprived regions. (© 2024 by the American Diabetes Association.)
Databáze:	MEDLINE
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